Protein Alignment NPFR and tacr3

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002934808.1
• Gene: tacr3 / 100486525
• XenbaseID: XB-GENE-985728
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 395
• Identity: 98/395 - (24%)
• Similarity: 161/395 - (40%)
• Gaps: 75/395 - (18%)

  Fly    10 PAQLADGEHLSGYASSSNSVRYLDDRHPLDYLDLGTVHALNTTAINTSDLNETGSRPLDPVLIDR 74
            |..|..||.:..:|.....|.:     |            |:|..|.|          .||
 Frog     5 PTNLTTGEVIGIFAPLGEGVLW-----P------------NSTQRNVS----------SPV---- 38

  Fly    75 FLSNRAVDSPWYHMLISM-YGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLV 138
              :::.|..||...|.|: ||.::.....||.:|:..::....|||..|.|::|||.||..:...
 Frog    39 --AHKFVQPPWRIALWSLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAF 101

  Fly   139 TMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGA 203
            ...:..:..|...|.:|..  .|:.........||.|..|::|||.|||..|:.|.:..|.....
 Frog   102 NTLVNFIYALHNEWYFGEA--YCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATST 164

  Fly   204 VTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCV 268
            ..::..||..|:|||.|..:|.::..|.|..|            |:..||.::.|..|....:.:
 Frog   165 KVVIGSIWIFAILLAFPQCLYSKIRVTRTRTL------------CMLVWPGKDERLTYQFILVLL 217

  Fly   269 QYLVPILIVSVAYFGIYNKLKSRITVVA-------VQASSAQRKVERGRRMKRTNCLLISIAIIF 326
            .|::|::::.|.|           |:|.       :...::.:..|:.|..::...::|.:.:.|
 Frog   218 VYVLPLIVMGVTY-----------TIVGITLWGGEIPGDTSDKYHEQLRAKRKVVKMMIVVVVTF 271

  Fly   327 GVSWLPLNFFNLYAD-----MERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQE 386
            .:.|||.:.|.| ||     ::|....|.:   |.....:.|||...||::|..||..||..|:.
 Frog   272 AICWLPYHIFFL-ADALDIKLDRWKYIQQI---YLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKR 332

  Fly   387 LLCRC 391
            ....|
 Frog   333 AFRWC 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	80/308 (26%)
		TM helix 1	88..114	CDD:320331	7/26 (27%)
		TM helix 2	121..146	CDD:320331	7/24 (29%)
		TM helix 3	161..191	CDD:320331	11/29 (38%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	6/28 (21%)
		TM helix 6	310..340	CDD:320331	8/29 (28%)
		TM helix 7	352..377	CDD:320331	7/24 (29%)
tacr3	XP_002934808.1	7tm_GPCRs	50..330	CDD:475119	80/308 (26%)
		TM helix 1	52..76	CDD:320669	6/23 (26%)
		TM helix 2	85..107	CDD:320669	7/21 (33%)
		TM helix 3	123..145	CDD:320669	6/21 (29%)
		TM helix 4	166..182	CDD:320669	6/15 (40%)
		TM helix 5	208..231	CDD:320669	5/33 (15%)
		TM helix 6	261..283	CDD:320669	6/21 (29%)
		TM helix 7	298..323	CDD:320669	8/27 (30%)