Protein Alignment NPFR and qrfprl2

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002935352.5
• Gene: qrfprl2 / 100486271
• XenbaseID: XB-GENE-952811
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 419
• Identity: 119/419 - (28%)
• Similarity: 202/419 - (48%)
• Gaps: 63/419 - (15%)

  Fly    49 LNTTAINTSDL----NET--------GSRPLDPVLIDRF-LSNRAVDSPWYHMLISMYGVLIVFG 100
            ||.|....|.|    |.|        |.:||  |.|... ||.:|:       .:.:|.::.:..
 Frog     5 LNITPETLSQLLKEHNMTRLQFIAAYGLKPL--VYIPELPLSAKAI-------FLVLYIIIFILA 60

  Fly   101 ALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIA 165
            ..||:|||..:|||..|||..|:||.::|.||||:....:|.||::.:|..|..|  ..:||.:.
 Frog    61 LFGNSLVVYIIIRKKAMRTVTNIFICSMACSDLLVTFFCIPFTLLQNISSEWLGG--RFVCKMVP 123

  Fly   166 MLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQF--VGAVTILAGIWALALLLASPLFVYKEL- 227
            .:|...:..||:::|.||.:|||.||:|.:...|:  :.|..:|..:|::|:::.||:...:.|
 Frog   124 FIQTTAVVASTLTMTCIAVERYQGIVHPLKMKRQYTNIRAYKMLGCVWSVAIVVGSPMLHVQTLE 188

  Fly   228 INTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYNKL--KS 290
            :..|....|..:       .|:|.|.....|..|:||.|...:|||:..:.:.|..|..:|  |.
 Frog   189 VKYDLLYNLYHV-------CCLESWSDVELRRAYAIFILVALFLVPLAAMLLLYTRIGYELWIKK 246

  Fly   291 RITVVAVQASSAQRKVER-GRRMKRTNCLLISIAIIFGVSWLPLNFFNL---YADM--ERSPVTQ 349
            |:...:|..:.::.::.: .|:.||...:::.:.:.|...|.|.:..::   |.::  |...||.
 Frog   247 RVGDCSVLNTLSRNEMAKITRKKKRAVMMMVIVVLFFTACWAPFHVVHILFEYNNLEDEYDDVTV 311

  Fly   350 SMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELL-C-------------RCSDTNVALNG 400
            .|:|  ||...:|..::.:||::|.::|:||:|....:| |             |.|..:....|
 Frog   312 KMIV--AIVQAVGFFNSFNNPVVYTFMNENFKKSLVAILFCHFRAQEPVEPADKRDSQQSERPKG 374

  Fly   401 HTTGCNVQAAARRRRKLG-AELSKGELKL 428
            .||    ...|||..:.| :.||...|:|
 Frog   375 GTT----MFFARRDGRSGQSHLSAENLEL 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	89/306 (29%)
		TM helix 1	88..114	CDD:320331	7/25 (28%)
		TM helix 2	121..146	CDD:320331	11/24 (46%)
		TM helix 3	161..191	CDD:320331	11/29 (38%)
		TM helix 4	202..223	CDD:320331	6/20 (30%)
		TM helix 5	258..287	CDD:320331	10/28 (36%)
		TM helix 6	310..340	CDD:320331	6/32 (19%)
		TM helix 7	352..377	CDD:320331	7/24 (29%)
qrfprl2	XP_002935352.5	7tmA_QRFPR	48..343	CDD:320333	88/312 (28%)
		TM helix 1	48..74	CDD:320333	7/32 (22%)
		TM helix 2	81..107	CDD:320333	11/25 (44%)
		TM helix 3	119..149	CDD:320333	11/29 (38%)
		TM helix 4	162..183	CDD:320333	6/20 (30%)
		TM helix 5	212..237	CDD:320333	9/24 (38%)
		TM helix 6	267..297	CDD:320333	6/29 (21%)
		TM helix 7	312..337	CDD:320333	8/26 (31%)