Protein Alignment NPFR and kissr1b

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001165295.1
• Gene: kissr1b / 100329184
• XenbaseID: XB-GENE-29077371
• Length: 367
• Species: Xenopus tropicalis
• Alignment Length: 238
• Identity: 46/238 - (19%)
• Similarity: 81/238 - (34%)
• Gaps: 72/238 - (30%)

  Fly    64 FDKNFNK----GLEWYREQMPETKFGEVTIEKSPAY---FHSKMAPERIKSLNPNTKIIIVVRDP 121
            :::.|||    |:.:     |:.|.||........|   .|....|.         |:||..:.|
 Frog   302 YERRFNKKLITGIIY-----PQNKDGEPEYNPCGKYMVKLHLNGVPR---------KVIIDDQLP 352

  Fly   122 VT---RAISDYTQSSSKRKRVGLMPSFETMAVGNCANWLRTNCTTKTRGVNAGWGAIRIGVYHKH 183
            |.   ..:..|:.:.|: ..|.|:.......:|. .::..:|.......: .||...||.::...
 Frog   353 VDHKGELLCSYSNNKSE-LWVSLIEKAYMKVMGG-YDFPGSNSNIDLHAL-TGWIPERIAMHSDS 414

  Fly   184 MKRWLDH---FPIENIHIVDGEKLISNPADEISATEKFLGLKPVAKPEKFGVDPIKKFPCIKNED 245
            .....|:   ...:..|  .|:.||:      ::|    |:...|:.||:|:.|...:..:
 Frog   415 QTFSKDNSFRMLYQRFH--KGDVLIT------AST----GMMTEAEGEKWGLVPTHAYAVL---- 463

  Fly   246 GKLHCLGKTKGRHHPDVEPSVLKTLREFYGPENKKFYQMINHW 288
                                   .:|||.|   .:|.|:.|.|
 Frog   464 -----------------------DIREFKG---LRFIQLKNPW 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	38/210 (18%)
		TM helix 1	88..114	CDD:320331	3/28 (11%)
		TM helix 2	121..146	CDD:320331	6/27 (22%)
		TM helix 3	161..191	CDD:320331	5/32 (16%)
		TM helix 4	202..223	CDD:320331	4/20 (20%)
		TM helix 5	258..287	CDD:320331	6/28 (21%)
		TM helix 6	310..340	CDD:320331
		TM helix 7	352..377	CDD:320331
kissr1b	NP_001165295.1	7tmA_KiSS1R	46..336	CDD:320223	9/38 (24%)
		TM helix 1	47..73	CDD:320223
		TM helix 2	80..106	CDD:320223
		TM helix 3	118..148	CDD:320223
		TM helix 4	160..180	CDD:320223
		TM helix 5	208..237	CDD:320223
		TM helix 6	261..291	CDD:320223
		TM helix 7	304..329	CDD:320223	8/29 (28%)