Protein Alignment NPFR and npy4r

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001106592.1
• Gene: npy4r / 100127810
• XenbaseID: XB-GENE-5848513
• Length: 371
• Species: Xenopus tropicalis
• Alignment Length: 355
• Identity: 112/355 - (31%)
• Similarity: 180/355 - (50%)
• Gaps: 44/355 - (12%)

  Fly    89 LISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWP 153
            |:..|..||..|.:||:.:|..:.|:..||...|:||.||:.||:|:.||.:|:|::..|...|.
 Frog    36 LVVAYSALIAVGLIGNSCLVFVIARQREMRNVTNIFIANLSCSDILMALVCLPVTVIYTLMNRWI 100

  Fly   154 YGSCSILCKTIAMLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLA 218
            .|..  |||....:|.:.:.||.:|:..||.:|:|:|::||........|...:|..||::..::
 Frog   101 LGEA--LCKVTNFVQCISVTVSVLSLVLIALERHQLIIHPTGWKPLPWHAYLAVAVTWAVSCFIS 163

  Fly   219 SPLFVYKELINTDTPALLQQIGLQDTIPY--------CIEDWPSRNGRFYYSIFSLCVQYLVPIL 275
            .|...:  .|.|..|  .|.:.|    |:        |.:.|||.|.|..|:...|..||.:|:|
 Frog   164 LPFLSF--TILTRHP--FQNLSL----PFDPFIDHFVCTDSWPSENHRLAYTTCLLLFQYCLPLL 220

  Fly   276 IVSVAYFGIYNKLKSRITVVAVQASSAQRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFFNLYA 340
            ::.:.|..|:.:|:.|..||. :|........:|.. :|.|.:|:||.:.||:.||||..||...
 Frog   221 LILLCYLRIFLRLRKRRDVVE-RAGGGDAGGRKGGH-RRVNVMLLSIVVAFGLCWLPLTVFNALF 283

  Fly   341 DMERSPVTQSM--LVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQELLCRCSDTNVALNGHTT 403
            |.:...::...  |: :::||:..|:|.|.||::||:||.||:||.:.:|.||.
 Frog   284 DWDHEQISACYHNLI-FSLCHLAAMASTCVNPVMYGFLNSNFQKEVKTILLRCR----------- 336

  Fly   404 GCNVQAAARRRRK------LGAELSKGELK 427
             |   |..|.|.:      :..|:||..|:
 Frog   337 -C---AGGRDRYESFPLSTVSTEVSKASLQ 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	100/304 (33%)
		TM helix 1	88..114	CDD:320331	8/24 (33%)
		TM helix 2	121..146	CDD:320331	12/24 (50%)
		TM helix 3	161..191	CDD:320331	10/29 (34%)
		TM helix 4	202..223	CDD:320331	5/20 (25%)
		TM helix 5	258..287	CDD:320331	9/28 (32%)
		TM helix 6	310..340	CDD:320331	13/29 (45%)
		TM helix 7	352..377	CDD:320331	10/24 (42%)
npy4r	NP_001106592.1	7tmA_NPY4R	34..328	CDD:320519	100/304 (33%)
		TM helix 1	35..61	CDD:320519	8/24 (33%)
		TM helix 2	68..93	CDD:320519	12/24 (50%)
		TM helix 3	106..136	CDD:320519	10/29 (34%)
		TM helix 4	147..168	CDD:320519	5/20 (25%)
		TM helix 5	203..232	CDD:320519	9/28 (32%)
		TM helix 6	253..283	CDD:320519	14/30 (47%)
		TM helix 7	296..321	CDD:320519	10/25 (40%)