Protein Alignment NPFR and tacr1

DIOPT Version :10

• Sequence 1: NP_001246947.1
• Gene: NPFR / 40754
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_001106489.1
• Gene: tacr1 / 100127678
• XenbaseID: XB-GENE-5835469
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 352
• Identity: 92/352 - (26%)
• Similarity: 156/352 - (44%)
• Gaps: 39/352 - (11%)

  Fly    49 LNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISM-YGVLIVFGALGNTLVVIAVI 112
            :|.:..|:|..|.||..  :..:::.||     ...|...|.|: |.::::...:||.:|:..::
 Frog     1 MNISMQNSSICNSTGGN--ETCIVNPFL-----QPAWQIALWSIAYSIIVIVSVVGNIIVMWIIL 58

  Fly   113 RKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIFVSTI 177
            ....|||..|.|::|||.::..:......:.....:..:|.||  .|.||.........:|.|..
 Frog    59 AHKRMRTVTNYFLVNLAFAEASMSAFNTVINFTYAIHNHWYYG--LIYCKFHNFFPISAVFSSIY 121

  Fly   178 SITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVYKELINTDTPALLQQIGLQ 242
            |:||||.|||..|::|.:..|.......::|.||..|..||.|...:..:  ..||
 Frog   122 SMTAIALDRYMAIIHPLKPRLSATATRIVIAVIWGFAFALAFPQGYFATV--EPTP--------- 175

  Fly   243 DTIPYCIEDWP-SRNGRF--YYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVA--VQASSA 302
            |.: .|..:|| |.|.:|  .|.:....:.|.:|:|::..:|..|      .:|:.|  :...|:
 Frog   176 DRV-VCYMEWPESENRKFEKVYQVLLFGLIYFLPLLVIGCSYTFI------GMTLWASEIPGDSS 233

  Fly   303 QRKVERGRRMKRTNCLLISIAIIFGVSWLPLNFF---NLYADMERSPVTQSMLVRYAICHMIGMS 364
            .|..|:....::...::|.:...|.:.|||.:.:   .|:...|.....|.:   |.....:|||
 Frog   234 DRYHEQVVAKRKVVKMMIVVVCTFAICWLPYHIYFLLQLFLPDESQKFYQQL---YLGIMWLGMS 295

  Fly   365 SACSNPLLYGWLNDNFRKEFQELLCRC 391
            |...||::|..|||.||..|:.:...|
 Frog   296 STMYNPIIYCCLNDRFRIGFKHVFRWC 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFR	NP_001246947.1	7tmA_NPYR-like	88..384	CDD:320331	81/304 (27%)
		TM helix 1	88..114	CDD:320331	6/26 (23%)
		TM helix 2	121..146	CDD:320331	5/24 (21%)
		TM helix 3	161..191	CDD:320331	12/29 (41%)
		TM helix 4	202..223	CDD:320331	7/20 (35%)
		TM helix 5	258..287	CDD:320331	7/30 (23%)
		TM helix 6	310..340	CDD:320331	6/32 (19%)
		TM helix 7	352..377	CDD:320331	8/24 (33%)
tacr1	NP_001106489.1	7tmA_NK1R	33..315	CDD:320668	81/304 (27%)
		TM helix 1	34..60	CDD:320668	6/25 (24%)
		TM helix 2	67..93	CDD:320668	5/25 (20%)
		TM helix 3	105..135	CDD:320668	12/29 (41%)
		TM helix 4	146..167	CDD:320668	7/20 (35%)
		TM helix 5	193..222	CDD:320668	6/34 (18%)
		TM helix 6	241..271	CDD:320668	5/29 (17%)
		TM helix 7	283..308	CDD:320668	9/27 (33%)