DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gasp and R02F2.4

DIOPT Version :9

Sequence 1:	NP_649611.2	Gene:	Gasp / 40745	FlyBaseID:	FBgn0026077	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_498171.1	Gene:	R02F2.4 / 175755	WormBaseID:	WBGene00019833	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	61/267 - (22%)
Similarity:	91/267 - (34%)	Gaps:	79/267 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GFYPHDTSCDKYWKCDNGVSELKTCGNGLAFDATDSKYLTENCDYLHNV-DCGDRTELEPPITTP 91
            |.||......::..|.:|.:....|...|.:...     .|.||:.||| :||:..| |...:..
Worm    31 GMYPLGACEPRFLACVSGEARYMDCPEDLVYHKN-----LEFCDWRHNVFECGEEGE-ENEFSGD 89

  Fly    92 HCSRLYG----IFPD-----------ENKCDVFWN--------------CWNGEPSRYQCSPGLA 127
            ......|    .|.|           ||.|:...:              |.:|.|....||..|.
Worm    90 GSGESSGDEEITFGDSSGESSGDELLENVCESLKDGVYSSGTCSSSYIICNSGSPRFLSCSTPLI 154

  Fly   128 YDRDARVCMWADQVPECKNEEVANGFSCPAAGELANAGSFSRHAHPEDCRK-YYICLEGVAREYG 191
            ||...:.|.|...:.||..   .:|..|.:.|.::.:          :|.. ::.|.||:|....
Worm   155 YDPTNKKCSWKGMIDECSQ---VSGEYCESDGNISKS----------ECSNVFFSCSEGIAHRRN 206

  Fly   192 CPIGTVFKIGDSDGTGNCEDPEDVPGCEDYYGDLDLKSIRKSEL------LAGLNSEGR------ 244
            ||...||    :....:|:.|::|..|.:           |||.      :.|..|.||
Worm   207 CPANLVF----NPAISSCDWPKNVMDCSE-----------KSEKPQNCGEVDGYFSFGRCSSSFS 256

  Fly   245 --TKGAP 249
              |.|.|
Worm   257 ACTNGIP 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gasp	NP_649611.2	ChtBD2	21..72	CDD:214696	9/43 (21%)
		CBM_14	97..144	CDD:366726	16/75 (21%)
		CBM_14	170..218	CDD:366726	12/48 (25%)
R02F2.4	NP_498171.1	CBM_14	25..74	CDD:279884	11/47 (23%)
		ChtBD2	117..165	CDD:214696	11/47 (23%)
		CBM_14	185..229	CDD:279884	12/57 (21%)
		ChtBD2	240..283	CDD:214696	7/24 (29%)
		CBM_14	310..361	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157821
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940