Protein Alignment CtsL3 and Ctsb

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_072119.2
• Gene: Ctsb / 64529
• RGDID: 621509
• Length: 339
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 74/277 - (26%)
• Similarity: 119/277 - (42%)
• Gaps: 74/277 - (26%)

  Fly   106 LTETVNYKRYDQITEGID----WRQYGYISPVGDQGTECLSCWAFSTSGVLEAHMAKKY-----G 161
            |.|.|.:.....:.|..|    |.....|:.:.|||: |.|||||   |.:|| |:.:.     |
  Rat    68 LPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGS-CGSCWAF---GAVEA-MSDRICIHTNG 127

  Fly   162 NL-VPLSPKHLVDCVPYP-NNGCSGGWVSVAFNYTRDHGIATKESY-------PY---------- 207
            .: |.:|.:.|:.|.... .:||:||:.|.|:|:....|:.:...|       ||
  Rat   128 RVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVN 192

  Fly   208 ---EPVSGE---------C------LWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSID 254
               .|.:||         |      .:|.|:..|..|..|   :..|:|:...:|..|||..:..
  Rat   193 GSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSV---SDSEKEIMAEIYKNGPVEGAFT 254

  Fly   255 HLHEEFDQYSGGVLSIPACRSKRQDLT--HSVLLVGFGTHRKWG-----DYWIIKNSYGTDWGES 312
             :..:|..|..||.     :.:..|:.  |::.::|      ||     .||::.||:..|||::
  Rat   255 -VFSDFLTYKSGVY-----KHEAGDVMGGHAIRILG------WGIENGVPYWLVANSWNVDWGDN 307

  Fly   313 GYLKLARNANNMCGVAS 329
            |:.|:.|..|: ||:.|
  Rat   308 GFFKILRGENH-CGIES 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410
		Peptidase_C1A	120..334	CDD:239068	71/263 (27%)
Ctsb	NP_072119.2	Peptidase_C1A_CathepsinB	81..328	CDD:239111	71/264 (27%)
		Propeptide_C1	26..65	CDD:462365