Protein Alignment CtsL3 and Ctsz

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_071720.1
• Gene: Ctsz / 64138
• MGIID: 1891190
• Length: 306
• Species: Mus musculus
• Alignment Length: 298
• Identity: 77/298 - (25%)
• Similarity: 121/298 - (40%)
• Gaps: 73/298 - (24%)

  Fly    56 VLAVESHNQLYLQGKVAFKMGLNKFSDT--DQRILFNYRSSIPAPLETSTNALTETVNYKRYDQI 118
            :||..:..:||      |:.|...:...  ||..|.. |.:.|.|.|           |.....:
Mouse    18 LLASAARARLY------FRSGQTCYHPIRGDQLALLG-RRTYPRPHE-----------YLSPADL 64

  Fly   119 TEGIDWRQ---YGYISPVGDQGTE--CLSCWAF-STSGVLEAHMAKKYG--NLVPLSPKHLVDCV 175
            .:..|||.   ..|.|...:|...  |.||||. |||.:.:....|:.|  ..:.||.::::||
Mouse    65 PKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDC- 128

  Fly   176 PYPNNG-CSGGWVSVAFNYTRDHGIATKESYPYEPVSGEC----------------------LWK 217
              .|.| |.||.....:.|...|||..:....|:....:|                      ||:
Mouse   129 --GNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWR 191

  Fly   218 SDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDHLHEEFDQYSGGVLSIPACRSKRQD--- 279
            .. ..|:|||       .|:.:||:..| ||::..| ...|....|:||:.      ::.||
Mouse   192 VG-DYGSLSG-------REKMMAEIYAN-GPISCGI-MATEMMSNYTGGIY------AEHQDQAV 240

  Fly   280 LTHSVLLVGFGTHRKWGDYWIIKNSYGTDWGESGYLKL 317
            :.|.:.:.|:|......:|||::||:|..|||.|::::
Mouse   241 INHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRI 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	6/30 (20%)
		Peptidase_C1A	120..334	CDD:239068	63/232 (27%)
Ctsz	NP_071720.1	Peptidase_C1A_CathepsinX	64..305	CDD:239149	63/234 (27%)