Protein Alignment CtsL3 and ctsbb

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001418075.1
• Gene: ctsbb / 569298
• ZFINID: ZDB-GENE-070323-1
• Length: 326
• Species: Danio rerio
• Alignment Length: 284
• Identity: 75/284 - (26%)
• Similarity: 122/284 - (42%)
• Gaps: 78/284 - (27%)

  Fly   106 LTETVNYKRYDQITEGID----WRQYGYISPVGDQGTECLSCWAF-STSGVLEAHMAKKYGNLVP 165
            |..||.:....::.:..|    |.....::.:.|||: |.||||| :...:.:.......|...|
Zfish    63 LPHTVKHSTNVKLPDSFDLRDQWPNCKTLNQIRDQGS-CGSCWAFGAVESISDRICIHSKGKQSP 126

  Fly   166 -LSPKHLVDCVPYPNNGCSGGWVSVAFNYTRDHGIATKESY-------PYE-------------P 209
             :|.:.|:.|......|||||:.:.|::|.|..|:.|...|       ||.             |
Zfish   127 EISAEDLLSCCDQCGFGCSGGFPAEAWDYWRRSGLVTGGLYNSDVGCRPYSIAPCEHHVNGTRPP 191

  Fly   210 VSGE---------CL------WKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDHLHEE 259
            .|||         |:      :|.|:..|:....|.   .|::::...:|..|||..:.. ::|:
Zfish   192 CSGEQDTPKCTGVCIPKYSVPYKQDKHFGSKVYNVP---SDQQQIMTELYTNGPVEAAFT-VYED 252

  Fly   260 FDQYSGGVLSIPACRSKRQDLT------HSVLLVGFGTHRKWGD-----YWIIKNSYGTDWGESG 313
            |..|..||.         |.||      |:|.::|      ||:     :|::.||:.:|||::|
Zfish   253 FPLYKSGVY---------QHLTGSALGGHAVKILG------WGEENGTPFWLVANSWNSDWGDNG 302

  Fly   314 YLKLARNANNMCG-----VASLPQ 332
            |.|:.| .::.||     ||.||:
Zfish   303 YFKILR-GHDECGIESEMVAGLPK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410
		Peptidase_C1A	120..334	CDD:239068	72/270 (27%)
ctsbb	NP_001418075.1	Propeptide_C1	23..60	CDD:462365
		Peptidase_C1A_CathepsinB	76..322	CDD:239111	69/266 (26%)