Protein Alignment CtsL3 and Cts7

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_062412.1
• Gene: Cts7 / 56092
• MGIID: 1860262
• Length: 331
• Species: Mus musculus
• Alignment Length: 347
• Identity: 121/347 - (34%)
• Similarity: 184/347 - (53%)
• Gaps: 51/347 - (14%)

  Fly    13 ILLLLVELGLTAVS---DTEWDQYKAKYNKQYR-NRDKYHRALYEQRVLAVESH---NQLYLQGK 70
            ||.|.|.|...|..   |.||:::|...::.|. ..:|..||::|..|..::.|   |.|::..
Mouse     9 ILCLGVALAAPAPDYNLDAEWEEWKRSNDRTYSPEEEKQRRAVWEGNVKWIKQHIMENGLWMNN- 72

  Fly    71 VAFKMGLNKFSD-TDQRILFNYRSSIPAPLETSTNALTETVNY---------KRYDQITEGIDWR 125
              |.:.:|:|.| |.:.:                ..|||:.:|         ||..:|...:|||
Mouse    73 --FTIEMNEFGDMTGEEM----------------KMLTESSSYPLRNGKHIQKRNPKIPPTLDWR 119

  Fly   126 QYGYISPVGDQGTECLSCWAFSTSGVLEAHMAKKYGNLVPLSPKHLVDC-VPYPNNGCSGGWVSV 189
            :.||::||..||: |.:|||||.:..:|..:.||.|.|:|||.::|:|| |.|...||.||....
Mouse   120 KEGYVTPVRRQGS-CGACWAFSVTACIEGQLFKKTGKLIPLSVQNLMDCSVSYGTKGCDGGRPYD 183

  Fly   190 AFNYTRDH-GIATKESYPYEPVSGECLWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSI 253
            ||.|.::: |:..:.:||||..:..|.::.:||...::.:..:.. :|..|.:.:...||:||:|
Mouse   184 AFQYVKNNGGLEAEATYPYEAKAKHCRYRPERSVVKVNRFFVVPR-NEEALLQALVTHGPIAVAI 247

  Fly   254 DHLHEEFDQYSGGVLSIPACRSKRQDLTHSVLLVGFG------THRKWGDYWIIKNSYGTDWGES 312
            |..|..|..|.||:...|.||  :..|.|.:||||:|      .:||   ||::|||:|..|||:
Mouse   248 DGSHASFHSYRGGIYHEPKCR--KDTLDHGLLLVGYGYEGHESENRK---YWLLKNSHGERWGEN 307

  Fly   313 GYLKLARNANNMCGVASLPQYP 334
            ||:||.|..||.||:||...||
Mouse   308 GYMKLPRGQNNYCGIASYAMYP 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	16/59 (27%)
		Peptidase_C1A	120..334	CDD:239068	88/221 (40%)
Cts7	NP_062412.1	Inhibitor_I29	29..87	CDD:214853	16/60 (27%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:18776147	33..50		3/16 (19%)
		Peptidase_C1A	113..329	CDD:239068	88/222 (40%)