Protein Alignment CtsL3 and ctsh

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: XP_031753756.1
• Gene: ctsh / 496748
• XenbaseID: XB-GENE-5820392
• Length: 330
• Species: Xenopus tropicalis
• Alignment Length: 348
• Identity: 120/348 - (34%)
• Similarity: 173/348 - (49%)
• Gaps: 55/348 - (15%)

  Fly    15 LLLVELGLTAVSDTEWDQYKAKYNKQYRNRDK--YHRALYEQRVLAVESHNQLYLQGKVAFKMGL 77
            ::::....:.:.|.||:.:|.||.|:|.:.:.  :.|..:|.....|..||||..||...:.|.:
 Frog    10 IIVMSASASNLLDEEWNTWKEKYEKKYASSEDELFRRKAWEVNWDKVTKHNQLADQGLKKYTMAM 74

  Fly    78 NKFSD-TDQRILFNYRSSI----------PAPLETSTNALTETVNYKRYD----QITEGIDWRQY 127
            |.|:| |.:.:  |.|:..          |||               ||:    :|::|:|||..
 Frog    75 NHFADMTSEEM--NSRNCFLPTHYPSKHKPAP---------------RYNVKHAKISKGVDWRDS 122

  Fly   128 GYISPVGDQGTECLSCWAFSTSGVLEAHMAKKYGNLVPLSPKHLVDCVPYPNNGCSGGWVSVAFN 192
            ..||||.:|| .|.|||||:|.|||||........|..||.:.||||.|. ::||.||:...|.:
 Frog   123 NCISPVKNQG-YCGSCWAFATVGVLEALHCLNGNELHNLSEQQLVDCDPI-DHGCCGGFPINAID 185

  Fly   193 YTRDHGIATKESYPYEPVSGECLWKSDRSAG-TLSGYVTLGNYDERELAEVVYNIGPVAVSIDHL 256
            |....||...|.|.||.....|.:.|..:.. .:|.|..|.|  |..:|..|...||:.|... :
 Frog   186 YITQEGIMKSEDYEYEEKQFYCRYDSSNAIQLNVSKYYVLPN--EENMASSVAKDGPITVGFG-V 247

  Fly   257 HEEFDQYSGGVLSIPACRSKRQDLTHSVLLVGFGT-HRKWG-----DYWIIKNSYGTDWGESGYL 315
            :.:|..||.|:.. ..|..:.   .|::::||:|| |.:.|     ||||||||:||:|||.|:.
 Frog   248 NRDFMLYSKGIFD-GECAPRP---NHAIIIVGYGTLHCEEGKDDGEDYWIIKNSWGTEWGEDGFG 308

  Fly   316 KLARNANNMCGV----ASLPQYP 334
            |:.|| .:|||:    |||...|
 Frog   309 KIMRN-KDMCGISEFAASLELKP 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	20/57 (35%)
		Peptidase_C1A	120..334	CDD:239068	89/224 (40%)
ctsh	XP_031753756.1	Inhibitor_I29	25..84	CDD:214853	20/58 (34%)
		Peptidase_C1A	117..324	CDD:239068	85/216 (39%)