Protein Alignment CtsL3 and Ctsw

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001019413.1
• Gene: Ctsw / 293676
• RGDID: 1309354
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 330
• Identity: 96/330 - (29%)
• Similarity: 154/330 - (46%)
• Gaps: 50/330 - (15%)

  Fly    33 YKAKYNKQYRNRDKYHRALYEQRVLAVESHNQLYLQ-------GKVAFKMGLNKFSD-TDQRI-- 87
            ::.::|:.|.|..:|.|.      |.:.:||....|       |...|  |...||| |::..
  Rat    43 FQIQFNRSYSNPAEYTRR------LGIFAHNLAQAQRLQEEDLGTAEF--GQTPFSDLTEEEFGQ 99

  Fly    88 LFNYRSSIPAPLETSTNALTETVNYKRY-DQITEGIDWRQY-GYISPVGDQGTECLSCWAFSTSG 150
            |:.::.   || |...| :.:.|..:|: :.:....|||:. ..||.:.:|| .|..|||.:.:.
  Rat   100 LYGHQR---AP-ERILN-MAKKVKSERWGESVPPTCDWRKVKNIISSIKNQG-NCRCCWAIAAAD 158

  Fly   151 VLEAHMAKKYGNLVPLSPKHLVDCVPYPNNGCSGGWVSVAF-NYTRDHGIATKESYPYE--PVSG 212
            .::.....|....|.:|.:.|:|| ....|||:||:|..|: ....:.|:|::|.||::  ....
  Rat   159 NIQTLWRIKTQQFVDVSVQELLDC-DRCGNGCNGGFVWDAYITVLNNSGLASEEDYPFQGHQKPH 222

  Fly   213 ECLWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDHLHEEFDQYSGGVLSIPACRSKR 277
            .||....|....:..:..|.: :|:.:|..:...||:.|:|:  .:....|..||:.........
  Rat   223 RCLADKYRKVAWIQDFTMLSS-NEQVIAGYLAIHGPITVTIN--MKLLQYYQKGVIKATPSTCDP 284

  Fly   278 QDLTHSVLLVGFG------------TH----RKWGDYWIIKNSYGTDWGESGYLKLARNANNMCG 326
            ..:.|||||||||            :|    |:...|||:|||:|.:|||.||.:|.| .||.||
  Rat   285 HLVNHSVLLVGFGKEKGGMQTGTLLSHSRKPRRSTPYWILKNSWGAEWGEKGYFRLYR-GNNTCG 348

  Fly   327 VASLP 331
            :|..|
  Rat   349 IAKYP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	16/59 (27%)
		Peptidase_C1A	120..334	CDD:239068	73/232 (31%)
Ctsw	NP_001019413.1	Inhibitor_I29	40..96	CDD:214853	16/60 (27%)
		Peptidase_C1	126..356	CDD:425470	73/234 (31%)