Protein Alignment CtsL3 and Ctsh

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_037071.1
• Gene: Ctsh / 25425
• RGDID: 2447
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 111/322 - (34%)
• Similarity: 169/322 - (52%)
• Gaps: 20/322 - (6%)

  Fly    19 ELGLTAVSDTEWDQYKAKYNKQYRNRDKYHR-ALYEQRVLAVESHNQLYLQGKVAFKMGLNKFSD 82
            ||.:.|:....:..:..::.|.|.:|:..|| .::......:::||    |....||||||:|||
  Rat    22 ELTVNAIEKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHN----QRNHTFKMGLNQFSD 82

  Fly    83 TD-QRILFNYRSSIPAPLE-TSTNALTETVNYKRYDQITEGIDWRQYG-YISPVGDQGTECLSCW 144
            .. ..|...|..|.|.... |.:|.|..|..|      ...:|||:.| .:|||.:||. |.|||
  Rat    83 MSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY------PSSMDWRKKGNVVSPVKNQGA-CGSCW 140

  Fly   145 AFSTSGVLEAHMAKKYGNLVPLSPKHLVDCVP-YPNNGCSGGWVSVAFNY-TRDHGIATKESYPY 207
            .|||:|.||:.:|...|.::.|:.:.||||.. :.|:||.||..|.||.| ..:.||..::||||
  Rat   141 TFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPY 205

  Fly   208 EPVSGECLWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDHLHEEFDQYSGGVLSIPA 272
            ...:|:|.:..:::...:...|.:...||..:.|.|....||:.:.: :.|:|..|..||.|..:
  Rat   206 IGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFE-VTEDFMMYKSGVYSSNS 269

  Fly   273 CRSKRQDLTHSVLLVGFGTHRKWGDYWIIKNSYGTDWGESGYLKLARNANNMCGVASLPQYP 334
            |......:.|:||.||:| .:....|||:|||:|::||.:||..:.| ..||||:|:...||
  Rat   270 CHKTPDKVNHAVLAVGYG-EQNGLLYWIVKNSWGSNWGNNGYFLIER-GKNMCGLAACASYP 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	17/56 (30%)
		Peptidase_C1A	120..334	CDD:239068	80/216 (37%)
Ctsh	NP_037071.1	Inhibitor_I29	33..88	CDD:462410	17/58 (29%)
		Peptidase_C1A	115..329	CDD:239068	80/217 (37%)