Protein Alignment CtsL3 and Ctsc

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_058793.1
• Gene: Ctsc / 25423
• RGDID: 2445
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 321
• Identity: 96/321 - (29%)
• Similarity: 152/321 - (47%)
• Gaps: 62/321 - (19%)

  Fly    44 RDKYHRALYEQRVLAVESHNQLYLQG-----------------KVAFKMGLNKFSDTDQRILFNY 91
            ::||...||        |||..:::.                 |::.: .|.:.|....|||
  Rat   160 QEKYSERLY--------SHNHNFVKAINSVQKSWTATTYEEYEKLSIR-DLIRRSGHSGRIL--- 212

  Fly    92 RSSIPAPLETSTNALTETVNYKRYDQITEGIDWRQ---YGYISPVGDQGTECLSCWAFSTSGVLE 153
             ...|||:   |:.:.:.:.     .:.|..|||.   ..::|||.:| ..|.||::|::.|:||
  Rat   213 -RPKPAPI---TDEIQQQIL-----SLPESWDWRNVRGINFVSPVRNQ-ESCGSCYSFASLGMLE 267

  Fly   154 AHMAKKYGN-LVP-LSPKHLVDCVPYPNNGCSGGW-VSVAFNYTRDHGIATKESYPYEPVSGECL 215
            |.:.....| ..| |||:.:|.|.||. .||.||: ..:|..|.:|.|:..:..:||......|.
  Rat   268 ARIRILTNNSQTPILSPQEVVSCSPYA-QGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK 331

  Fly   216 WKSDRSAGTLSGYVTLGNY----DERELAEVVYNIGPVAVSIDHLHEEFDQYSGGV-----LSIP 271
            .|.:......|.|..:|.:    :|..:...:...||:||:.: :|::|..|..|:     ||.|
  Rat   332 PKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFE-VHDDFLHYHSGIYHHTGLSDP 395

  Fly   272 ACRSKRQDLT-HSVLLVGFGTHRKWG-DYWIIKNSYGTDWGESGYLKLARNANNMCGVASL 330
               ....:|| |:|||||:|.....| ||||:|||:|:.||||||.::.|..:. |.:.|:
  Rat   396 ---FNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDE-CAIESI 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	10/57 (18%)
		Peptidase_C1A	120..334	CDD:239068	79/228 (35%)
Ctsc	NP_058793.1	CathepsinC_exc	25..138	CDD:462598
		Pox_I6	168..>204	CDD:333259	6/44 (14%)
		Peptidase_C1A_CathepsinC	230..459	CDD:239112	79/230 (34%)