Protein Alignment CtsL3 and Y65B4A.2

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001293246.1
• Gene: Y65B4A.2 / 171655
• WormBaseID: WBGene00022026
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 91/401 - (22%)
• Similarity: 146/401 - (36%)
• Gaps: 105/401 - (26%)

  Fly     9 VHGLILLLLVELGLTAVSDTEWDQYKAKYNKQYRNRDKYHRALYEQRVLAVESHNQLYLQGKVAF 73
            :..:|||||..|||...|...:.:|....|.: |:.|:|.|.|..|...:.|:          .:
 Worm    56 IASVILLLLAVLGLVYGSFYLYRRYVTDANDK-RDNDEYLRKLVRQVNDSPET----------TW 109

  Fly    74 KMGLNKFSDTDQRILFNYRSSIPAPLE------------TSTNALTETVNYKRYDQITEGID--- 123
            |...|||...::...|.|..:..|..|            .....|.|..|:...| :.:..|
 Worm   110 KAKFNKFGVKNRSYGFKYTRNQTAVEEYVEQIRKFFESDAMKRHLDELENFNSSD-VPKNFDARQ 173

  Fly   124 -WRQYGYISPVGDQGTECLSCWAFSTSGVLE----AHMAKKYGNLVPLSPKHLVDCVPYPNNGCS 183
             |.....||.|.:|| .|.||:|.:.:||..    .|....:.:|  ||.:.::.|.....| |.
 Worm   174 KWPNCPSISNVPNQG-GCGSCFAVAAAGVASDRACIHSNGTFKSL--LSEEDIIGCCSVCGN-CY 234

  Fly   184 GGWVSVAFNYTRDHGIATK-----ESYPYEPVSG---------------ECL-----------WK 217
            ||....|..|..:.|:.|.     ..|.::...|               .|:           ::
 Worm   235 GGDPLKALTYWVNQGLVTGGRDGCRPYSFDLSCGVPCSPATFFEAEEKRTCMKRCQNIYYQQKYE 299

  Fly   218 SDRSAGTL--SGY-----------------VTLGNYDERE------------LAEVVYNIGPVAV 251
            .|:...|.  |.|                 ..:|::::::            :.:.:...||..:
 Worm   300 EDKHFATFAYSMYPRSMTVSPDGKERVKVPTIIGHFNDKKTEKLNVTEYRDIIKKEILLYGPTTM 364

  Fly   252 SIDHLHEEFDQYSGGVLSIPACRSKRQD---LTHSVLLVGFGTHRKWGDYWIIKNSYGTDWGESG 313
            :.. :.|||..||.||.. |.......|   ..|.|.|:|:|.......||:..||:|..||::|
 Worm   365 AFP-VPEEFLHYSSGVFR-PYPTDGFDDRIVYWHVVRLIGWGESDDGTHYWLAVNSFGNHWGDNG 427

  Fly   314 YLKLARNANNM 324
            ..|:  |.::|
 Worm   428 LFKI--NTDDM 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	13/54 (24%)
		Peptidase_C1A	120..334	CDD:239068	61/278 (22%)
Y65B4A.2	NP_001293246.1	Peptidase_C1A_CathepsinB	166..444	CDD:239111	61/279 (22%)