DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11459 and CTSZ

DIOPT Version :9

Sequence 1:NP_001287191.1 Gene:CG11459 / 40741 FlyBaseID:FBgn0037396 Length:336 Species:Drosophila melanogaster
Sequence 2:NP_001327.2 Gene:CTSZ / 1522 HGNCID:2547 Length:303 Species:Homo sapiens


Alignment Length:265 Identity:74/265 - (27%)
Similarity:108/265 - (40%) Gaps:75/265 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 RSSIPAPLETSTNALTETVNYKRYDQITEGIDWRQ---YGYISPVGDQGTE--CLSCWAF-STSG 150
            ||:.|.|.|           |.....:.:..|||.   ..|.|...:|...  |.||||. |||.
Human    47 RSTYPRPHE-----------YLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSA 100

  Fly   151 VLEAHMAKKYG--NLVPLSPKHLVDCVPYPNNG-CSGGWVSVAFNYTRDHGIATKESYPYEPVSG 212
            :.:....|:.|  ....||.::::||   .|.| |.||.....::|...|||..:....|:....
Human   101 MADRINIKRKGAWPSTLLSVQNVIDC---GNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQ 162

  Fly   213 EC----------------------LWKSDRSAGTLSGYVTLGNYDERELAEVVYNIGPVAVSIDH 255
            ||                      ||:.. ..|:|||       .|:.:||:..| ||::..| .
Human   163 ECDKFNQCGTCNEFKECHAIRNYTLWRVG-DYGSLSG-------REKMMAEIYAN-GPISCGI-M 217

  Fly   256 LHEEFDQYSGGVLSIPACRSKRQDLT---HSVLLVGFGTHRKWG-----DYWIIKNSYGTDWGES 312
            ..|....|:||:.      ::.||.|   |.|.:.|      ||     :|||::||:|..|||.
Human   218 ATERLANYTGGIY------AEYQDTTYINHVVSVAG------WGISDGTEYWIVRNSWGEPWGER 270

  Fly   313 GYLKL 317
            |:|::
Human   271 GWLRI 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11459NP_001287191.1 Inhibitor_I29 30..85 CDD:285458
Peptidase_C1A 120..334 CDD:239068 68/237 (29%)
CTSZNP_001327.2 Peptidase_C1A_CathepsinX 62..302 CDD:239149 68/239 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1275401at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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