Protein Alignment CtsL3 and Ctsw

DIOPT Version :10

• Sequence 1: NP_649608.1
• Gene: CtsL3 / 40741
• FlyBaseID: FBgn0037396
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_034115.2
• Gene: Ctsw / 13041
• MGIID: 1338045
• Length: 371
• Species: Mus musculus
• Alignment Length: 363
• Identity: 104/363 - (28%)
• Similarity: 166/363 - (45%)
• Gaps: 64/363 - (17%)

  Fly    13 ILLLLVELGLTAVSDTE------------WDQYKAKYNKQYRNRDKYHRALYEQRVLAVESHNQL 65
            ::|||...||:....|:            :..::.::|:.|.|..:|.|.      |::.:||..
Mouse    11 LVLLLAGQGLSDSLLTKDAGPRPLELKEVFKLFQIRFNRSYWNPAEYTRR------LSIFAHNLA 69

  Fly    66 YLQ-------GKVAFKMGLNKFSDTDQRILFNYRSSIPAPLETSTNALTETVNYKRY-DQITEGI 122
            ..|       |...|  |...|||..:...........:|..|..  :|:.|....: :.:....
Mouse    70 QAQRLQQEDLGTAEF--GETPFSDLTEEEFGQLYGQERSPERTPN--MTKKVESNTWGESVPRTC 130

  Fly   123 DWRQ-YGYISPVGDQGTECLSCWAFSTSGVLEAHMAKKYGNLVPLSPKHLVDCVPYPNNGCSGGW 186
            |||: ...||.|.:||: |..|||.:.:..::|....|:...|.:|.:.|:|| ....|||:||:
Mouse   131 DWRKAKNIISSVKNQGS-CKCCWAMAAADNIQALWRIKHQQFVDVSVQELLDC-ERCGNGCNGGF 193

  Fly   187 VSVAF-NYTRDHGIATKESYPYEPVSGE-----CLWKSDRSAGTLSGYVTLGNYDERELAEVVYN 245
            |..|: ....:.|:|:::.||::   |:     ||.|..:....:..:..|.| :|:.:|..:..
Mouse   194 VWDAYLTVLNNSGLASEKDYPFQ---GDRKPHRCLAKKYKKVAWIQDFTMLSN-NEQAIAHYLAV 254

  Fly   246 IGPVAVSIDHLHEEFDQYSGGVL-SIPACRSKRQDLTHSVLLVGFG------------TH----R 293
            .||:.|:|:  .:....|..||: :.|:....|| :.|||||||||            :|    |
Mouse   255 HGPITVTIN--MKLLQHYQKGVIKATPSSCDPRQ-VDHSVLLVGFGKEKEGMQTGTVLSHSRKRR 316

  Fly   294 KWGDYWIIKNSYGTDWGESGYLKLARNANNMCGVASLP 331
            ....|||:|||:|..|||.||.:|.| .||.|||...|
Mouse   317 HSSPYWILKNSWGAHWGEKGYFRLYR-GNNTCGVTKYP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL3	NP_649608.1	Inhibitor_I29	30..85	CDD:462410	15/61 (25%)
		Peptidase_C1A	120..334	CDD:239068	79/236 (33%)
Ctsw	NP_034115.2	Inhibitor_I29	40..96	CDD:214853	15/63 (24%)
		Peptidase_C1A	127..356	CDD:239068	79/237 (33%)