DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10280 and Nrx-IV

DIOPT Version :10

Sequence 1:NP_001246942.1 Gene:CG10280 / 40740 FlyBaseID:FBgn0037395 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_524034.2 Gene:Nrx-IV / 39387 FlyBaseID:FBgn0013997 Length:1284 Species:Drosophila melanogaster


Alignment Length:360 Identity:73/360 - (20%)
Similarity:110/360 - (30%) Gaps:136/360 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 GVDFFEHEFTSVAEVL-----KPLSDEYDPY--GP--DIGDD-----------DLGIDDPETMPR 119
            |.|..|.|:..|..|.     .||.::...|  ||  ..|||           |..|:.| ....
  Fly   751 GGDIREKEYLPVRAVKFGDTGTPLDEKMGRYTLGPLRCEGDDLFSNVVTFRIADASINLP-PFDM 814

  Fly   120 LFQGDI---------------AIDPYTYITLRL------------GVNPM--------------- 142
            ...|||               |..|..||.|.|            |..|:               
  Fly   815 GHSGDIYLEFRTTQENSVIFHATGPTDYIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNW 879

  Fly   143 --------RHPKRLWPNGTIPFEISP-----RYANQERQAIIQAVKTFNS--LTCVHFVPYDGEV 192
                    |...||..:|:|..|:..     |..:.....:|.|...:..  :.|:..:..:|::
  Fly   880 HTVSVERNRKEARLVVDGSIKAEVREPPGPVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKM 944

  Fly   193 DDYLLIEPPLEG----PQGCWSYVGRRGGEQVVS----LQRPDENSAHCFSS--EGRIMHELMHA 247
            .|  |.|....|    ..||   |||......::    ::|.|..|..|..|  :|.|..:   .
  Fly   945 VD--LKEYSKRGLYGISTGC---VGRCESNPCLNNGTCIERYDGYSCDCRWSAFKGPICAD---E 1001

  Fly   248 IGIYHEQSRADRDNF-----------VKIHWDNIVPRFRKNFKL--VSKKKGKY----------- 288
            ||:....|...|..|           :::.:...:|   |.|.|  .|...|:|           
  Fly  1002 IGVNLRSSSIIRYEFEGSFRSTIAENIRVGFTTTIP---KGFLLGFSSNLTGEYLTIQISNSGHL 1063

  Fly   289 --AFDYDYN------SVMHYG-----EFYFSKRKG 310
              .||:.:.      ...|:|     :.:|.::.|
  Fly  1064 RCVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNG 1098

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10280NP_001246942.1 ZnMc_astacin_like 151..342 CDD:239807 42/214 (20%)
Nrx-IVNP_524034.2 FA58C 57..184 CDD:238014
LamG 192..340 CDD:238058
LamG 376..514 CDD:238058
EGF 546..575 CDD:394967
LamG 819..943 CDD:214598 20/123 (16%)
EGF_CA 966..998 CDD:238011 6/31 (19%)
Laminin_G_2 1032..1156 CDD:460494 13/70 (19%)
4.1m 1239..1255 CDD:128590
Blue background indicates that the domain is not in the aligned region.

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