DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10280 and Cubn

DIOPT Version :9

Sequence 1:NP_001246942.1 Gene:CG10280 / 40740 FlyBaseID:FBgn0037395 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_727348.2 Gene:Cubn / 326235 FlyBaseID:FBgn0052702 Length:3750 Species:Drosophila melanogaster


Alignment Length:388 Identity:74/388 - (19%)
Similarity:117/388 - (30%) Gaps:108/388 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 CGVERVGKQRSNGNIVTAKPNPSSIMCAQLSGSVVLLVQLQVAVLLVALLVLSATTLSESAKLPV 69
            ||.....|:.:.....||...|..:.|..   .:.|.|..||.:....|                
  Fly   744 CGGVYTAKEGTISESSTANTEPGGVSCEY---EIHLAVGEQVVIQFARL---------------- 789

  Fly    70 RQYPAGVDFFEHEFTSVAEVLKPLSDEYDPYGPDIGDDDLGIDDPETMPRLFQGD---IAIDPYT 131
                      |.:.....|||    |..|..|..:.:...|.|.....|..|..:   :.|..|.
  Fly   790 ----------ELDPLDCLEVL----DITDEGGSILQEKICGSDASRLNPPTFTSEFNRLKIKFYA 840

  Fly   132 -----YITLRLGVNPMRHPKRLWPNGTIPFEISPRYANQERQ------AIIQAVKTFNSLTCVHF 185
                 .:..|:..:...:.::    |||   .||.|.|..|.      .|..|..|..||..:.|
  Fly   841 RAGSFQLNYRMACDYKLNNEQ----GTI---TSPGYPNLTRSDRICTYTISTATNTVISLKRIDF 898

  Fly   186 VPYDGEVDDYLLIEPPLEGPQGCWSYVGRRGGEQVVSLQRPDENSAHCFSSEGRIMHELMHAI-G 249
            ...:||.||                                |:|. .|.::..||...|...| |
  Fly   899 QLTNGESDD--------------------------------DDND-ECLTTNLRINDGLNRKILG 930

  Fly   250 IY-----HEQSRADRDNFVKIHWDNIVPRFRKNFKLV--------SKKKGKYAFDYDYNSVMHYG 301
            .|     .|::.....|::::|....|....:.||..        .|..|.:....|:..:..:.
  Fly   931 PYCGKNQPEENFVSETNYLQLHLSTDVDSMGRGFKFEYRALATGNDKCGGVHTRSGDHIRLPVHD 995

  Fly   302 EFYFSKRKGEKPTMTPLQPGVRI--GQRKTISKIDC----LKINELYGC-LQGRRAKMYRSFC 357
            :.|..:.......|.|....:|:  ......:.:||    |:|.:..|. :...|:|....:|
  Fly   996 DSYAGEATCYWVIMAPANKAIRLHWNSFSLENAVDCIYDYLEIYDSLGAQVNDERSKPLAKYC 1058

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10280NP_001246942.1 Astacin 147..344 CDD:279708 44/222 (20%)
ZnMc_astacin_like 151..342 CDD:239807 44/216 (20%)
CubnNP_727348.2 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 282..322 CDD:214542
EGF_3 328..366 CDD:289699
EGF 430..457 CDD:278437
EGF_CA 469..503 CDD:238011
CUB 509..622 CDD:238001
CUB 627..737 CDD:238001
CUB 744..849 CDD:294042 25/137 (18%)
CUB 853..970 CDD:238001 33/156 (21%)
CUB 978..1094 CDD:238001 14/81 (17%)
CUB 1100..1211 CDD:238001
CUB 1216..1330 CDD:238001
CUB 1446..1549 CDD:238001
CUB 1554..1667 CDD:238001
CUB 1792..1899 CDD:238001
CUB 1910..1998 CDD:294042
CUB 2019..2133 CDD:238001
CUB 2140..2242 CDD:238001
CUB 2263..2379 CDD:238001
CUB 2385..2511 CDD:238001
CUB 2516..2630 CDD:238001
CUB <2833..2892 CDD:294042
CUB 2898..3008 CDD:238001
CUB 3011..3127 CDD:238001
CUB 3130..3241 CDD:238001
CUB 3254..3363 CDD:238001
CUB 3379..3508 CDD:238001
CUB 3531..3601 CDD:294042
CUB 3623..3733 CDD:238001
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45444884
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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