Protein Alignment Rm62 and DBP2

DIOPT Version :10

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_014287.3
• Gene: DBP2 / 855611
• SGDID: S000005056
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 563
• Identity: 307/563 - (54%)
• Similarity: 371/563 - (65%)
• Gaps: 36/563 - (6%)

  Fly   165 GGDDRRGGGGGGNRFGGGGGGGDYHGIRNGRVEKRRDDRGGGNRFGGGGGFGDRRGGGGGGS--- 226
            ||.|::     .|:......|||:.|.||       .||...|....||.:   |||.||.|
Yeast     4 GGRDQQ-----YNKTNYKSRGGDFRGGRN-------SDRNSYNDRPQGGNY---RGGFGGRSNYN 53

  Fly   227 --QDL--PMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYREEQEITVRG-QVPNPIQDFSEV 286
              |:|  |....:...|..|:||||.||.:|.:||..|:.::|:|.|:|:.| .:|.||..|.|.
Yeast    54 QPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISGHDIPKPITTFDEA 118

  Fly   287 HLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQR 351
            ..||||:.|::.:|:..||.||.||||:|:||.:.||||.|||||||.|.||.|||||.|..|..
Yeast   119 GFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAP 183

  Fly   352 GDGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLI 416
            |||||.||||||||||.|||...::||.||.:|||||:||.||..|:|||.||.|||||||||||
Yeast   184 GDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLI 248

  Fly   417 DFLSAGSTNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFL 481
            |.|..|.|||||.||||||||||||||||||||||||.|||||||||||||||||||||||.|:|
Yeast   249 DMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYL 313

  Fly   482 GNYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNL 546
            .:.||:.:|||||||:|||.|:|:|..:|.|.::|...|......:|.  |.:||..|||..|::
Yeast   314 NDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEY--KTLIFASTKRMCDDI 376

  Fly   547 VRFIRSFGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNS 611
            .:::|..|....||||||.|.|||:||:|||:|:|.|:|||||||||:||.||.||||:|.|.|.
Yeast   377 TKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNI 441

  Fly   612 EDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALENLARNSRYDGGGGRS 676
            |||:||||||||:...||:.:|||:.|......|:.::|||||.|.|.|....|.|.   |||..
Yeast   442 EDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYDRRSY---GGGHP 503

  Fly   677 RYGGGGGGGRFGGGGFKKGSLSNGRGFGGG-----GGGGGEGR 714
            |||||.||   .||..::|....|||..||     ||.|..||
Yeast   504 RYGGGRGG---RGGYGRRGGYGGGRGGYGGNRQRDGGWGNRGR 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	260/438 (59%)
DBP2	NP_014287.3	DEAD-like_helicase_N	4..492	CDD:475120	282/504 (56%)