DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rm62 and ddx21

DIOPT Version :9

Sequence 1:	NP_524243.2	Gene:	Rm62 / 40739	FlyBaseID:	FBgn0003261	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001039224.1	Gene:	ddx21 / 734085	XenbaseID:	XB-GENE-1012547	Length:	755	Species:	Xenopus tropicalis

Alignment Length:	436	Identity:	139/436 - (31%)
Similarity:	225/436 - (51%)	Gaps:	50/436 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 EVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNF 321
            |.|..:||:||.   :.|       |||:..:....:|.::.:|......||::.:..|.||.:.
Frog   162 EKQLTKEEEEINQEKIDG-------DFSKFPISKDTIKNLQAKGVSYLFPIQSKTFHTAYSGKDV 219

  Fly   322 VGIAKTGSGKTLGYILPAIVHIN-NQQPLQRGDGPIALVLAPTRELAQQIQQVATEFGS-SSYVR 384
            |..|:||:|||..:.:|.:..:| :||||.||..|..::|.||||||.||   ..|..| :..::
Frog   220 VVQARTGTGKTFSFAIPLVERLNEDQQPLARGRAPRVIILTPTRELAIQI---TNEIRSITKKLK 281

  Fly   385 NTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMGFEPQI 449
            ..|.:||.|...|:..::.|.:.::.||||:.|.:.....:|....::||||.|.|.||||..|:
Frog   282 VCCFYGGTPYQQQVFSIKEGFDFLVGTPGRVRDLVQNYRLDLTVLKHVVLDEVDMMFDMGFSEQV 346

  Fly   450 RKIVS-QIRPD----RQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANHNIRQVVDV--- 506
            .:|:| :.:||    .|||::|||.|..:..:|:    .|::.....::|..:.:.:..:.|
Frog   347 EEILSVRYKPDPEENPQTLLFSATCPDWMYNVAK----KYMKKQFEKIDLVGHRSQKAAITVEHL 407

  Fly   507 CDEFSKEEKLKTLLSDIYDT-SESPGKIIIFVETKRRVDNLVRFIRSFGVRCGA-------IHGD 563
            ..|.::.:| ..:|.||... |.|.||.|||.::|.....|       ...||:       :|||
Frog   408 AIECTRSQK-AAVLGDIVQVYSGSHGKSIIFCDSKLEAHEL-------ATNCGSLKQSAKPLHGD 464

  Fly   564 KSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKG 628
            ..|.||:.:|:.||.|...:||||:|||||||:..:..|:.:..|:.::.|:||.|||||:...|
Frog   465 LQQKEREVILKGFRQGSFEVLVATNVAARGLDIPEVDLVVLYSAPKEADAYVHRSGRTGRAGRTG 529

  Fly   629 TSFAFFTKNNAKQAKALVDVLREANQEIN----PALENLARNSRYD 670
            ...:.:   ..::...|.:|.|.......    |:|.|:|::|..|
Frog   530 ICISLY---EPRERHYLRNVERSTGITFKRVGIPSLLNVAKSSSAD 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	PTZ00424	280..656	CDD:185609	126/393 (32%)
		DEADc	283..488	CDD:238167	72/211 (34%)
		HELICc	499..633	CDD:238034	49/144 (34%)
ddx21	NP_001039224.1	PRK01297	83..551	CDD:234938	133/413 (32%)
		DEADc	181..385	CDD:238167	72/210 (34%)
		HELICc	404..534	CDD:238034	49/137 (36%)
		GUCT_RHII_Gualpha_beta	611..703	CDD:240593
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000