Protein Alignment Rm62 and ddx4

DIOPT Version :10

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: XP_012818309.1
• Gene: ddx4 / 549577
• XenbaseID: XB-GENE-1016809
• Length: 678
• Species: Xenopus tropicalis
• Alignment Length: 681
• Identity: 219/681 - (32%)
• Similarity: 332/681 - (48%)
• Gaps: 96/681 - (14%)

  Fly    63 SSLCTEQRQQFHGSRRNRETILFPSTYSSLQAQSQRAF-------RDSSKPDSDDYVDSIPKAEQ 120
            |||.|:....:.....|..|        :...||:|:|       .:...|.:.:....|.:...
 Frog    21 SSLETDNTDNYTAYSNNDIT--------NQNYQSERSFGNRGGYRSERGGPTNFNRGSRIGRGRG 77

  Fly   121 RTRTRKSLFNDPDERTEEIKIEGVMAPHDRDFGHSGRGGRGGDRGGDDRRG-GGGGGNRFGGGG- 183
            ....|...::|..||      :|..|..|......||||...:.|  .||| |..||.|...|.
 Frog    78 FDSNRNDQYSDSSER------DGYNANEDTQKPFRGRGGFRNENG--QRRGFGDRGGFRNENGQQ 134

  Fly   184 ---GGGDYHGIRNGRVEKRRDDRGGGNRF----GGGGGFGDRRGGGG------------GGSQD- 228
               ..||::....|....|...|||.|.|    ||.|..|.|.|.||            |.:|:
 Frog   135 RNFDRGDWNNSGEGEERPRGFGRGGFNNFDSDTGGRGHRGGRGGRGGYKGRNEEVGVESGKNQEE 199

  Fly   229 -----------LPMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYREEQEITVRGQ-VPNPIQ 281
                       :|:.|.|..:      :.::.:.:..|...|      :|..:.|.|: ||..|.
 Frog   200 GTEKEVKKVIYVPLPPSDSED------DIFRHYQSGINFDKY------DEILVDVTGKDVPPAIL 252

  Fly   282 DFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQ 346
            .|.|.:..:.:.:.:.:.||...|.:|....||.::|.:.:..|:||||||..::||.:.|:.|:
 Frog   253 TFEEANFCETLSRNVTKAGYVKLTPVQKHSIPIILAGRDLMACAQTGSGKTAAFLLPILSHMMNE 317

  Fly   347 -------QPLQRGDGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRG 404
                   .|||.   |.|:::||||||..||...|.:|...:.||...|:||......|||::||
 Frog   318 GITASQFLPLQE---PQAIIIAPTRELINQIYLDARKFSYGTCVRPVVVYGGIHPVHAMRDVERG 379

  Fly   405 CEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQ----IRPDRQTLMW 465
            |.|:.||||||:|.:......|.:..|||||||||||||||.|.:..::..    .:.:|||||:
 Frog   380 CNILCATPGRLMDIIGREKIGLSKLKYLVLDEADRMLDMGFAPVMENLIGSPGMPAKEERQTLMF 444

  Fly   466 SATWPKEVKQLAEDFL-GNYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSES 529
            |||:|.|:::||..|| .:::.:.:| |...|..::.|.:....|:.|.:||..:|.     |..
 Frog   445 SATYPAEIQRLASKFLKSDHLFVVVG-LVGGACSDVEQTILEIQEYRKRDKLVEILQ-----SSG 503

  Fly   530 PGKIIIFVETKRRVDNLVRFIRSFGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGL 594
            ..:.:|||.||::.|.:..::........:||||:.|.:|:..:|:|||||..::|.|.||||||
 Frog   504 NERTMIFVNTKKKADVIAGYLCQEHFPTTSIHGDREQCQREEAIRDFRSGKCPVIVCTAVAARGL 568

  Fly   595 DVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKN-NAKQAKALVDVLREANQEINP 658
            |::.:::|||:|.|:..::|:||||||||....|.:.:||..| :...|:.||.:|.:|:||:..
 Frog   569 DIENVQHVINYDVPKEIDEYVHRIGRTGRCGNVGKATSFFNVNEDHVVARPLVKILTDAHQEVPA 633

  Fly   659 ALENLARNSRYDGGGG-RSRYGGGGGGGRFG 688
            .||.:|    :.|.|. .|.|.....||..|
 Frog   634 WLEEIA----FGGHGALNSLYAADSMGGEAG 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	160/451 (35%)
ddx4	XP_012818309.1	DEADc_DDX4	210..473	CDD:350810	98/278 (35%)
		SF2_C_DEAD	479..608	CDD:350174	49/133 (37%)