DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rm62 and CG5800

DIOPT Version :9

Sequence 1:	NP_524243.2	Gene:	Rm62 / 40739	FlyBaseID:	FBgn0003261	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	134/472 - (28%)
Similarity:	215/472 - (45%)	Gaps:	58/472 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 GNRFGGGGGFGDRRGGG---GGGSQDLPMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQ----R 263
            |:||..|.|.....|||   |..||..|.:.::.|.||               .:..|:|    :
  Fly    13 GSRFKPGSGTFKGAGGGRKSGDNSQKRPRQEINKSRLA---------------ATEAEIQDLKTK 62

  Fly   264 YREEQEITVRGQVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTG 328
            |.|..        ...|:.|::..|.....|.:....:..||.:|......|:.|.:.:|.|.||
  Fly    63 YAEID--------ATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITG 119

  Fly   329 SGKTLGYILPAIVHINNQQPLQRGDGPIALVLAPTRELAQQIQQVATEFGSSSYVRNTCVFGGAP 393
            |||||.:::|.:.|: ......|.||..|::::||||||.||.:...:.|.........:.||..
  Fly   120 SGKTLAFLIPVLEHL-FMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKN 183

  Fly   394 KGGQMRDLQRGCEIVIATPGRLIDFLSAGST-NLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIR 457
            ...:...:.: |.|:|.|||||:..:..... |......||||||||.|||||:..:..|:....
  Fly   184 LKFERTRMDQ-CNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFP 247

  Fly   458 PDRQTLMWSATWPKEVKQLAEDFLGNYIQINIG----------SLELSANHNIRQVVDVCDE--- 509
            |.||||::|||....|:.||...|.:.:.:..|          |.:.:.|..:..|.::..:
  Fly   248 PVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQQSYV 312

  Fly   510 -FSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFIRSFGVRCG----AIHGDKSQSER 569
             .:.|:|:..|.|.|.:..:.  |||:||.:.::...|......  :|.|    |::|...|..|
  Fly   313 VLNLEDKITMLWSFIKNHLKQ--KIIVFVASCKQAKYLYEIFCK--LRPGSPLLALYGTLHQDRR 373

  Fly   570 DFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFF 634
            ..:..:|......::.:||||:||||...:.:|:..|.|::...||||.||:.|:.|:|......
  Fly   374 IAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVL 438

  Fly   635 TKNNAKQAKALVDVLRE 651
            |.:   :.:.::..|:|
  Fly   439 TPS---EEEYMISALKE 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	PTZ00424	280..656	CDD:185609	115/391 (29%)
		DEADc	283..488	CDD:238167	69/205 (34%)
		HELICc	499..633	CDD:238034	39/141 (28%)
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	134/472 (28%)
		DEADc	74..277	CDD:238167	69/204 (34%)
		HELICc	311..437	CDD:238034	38/129 (29%)
		DUF4217	474..530	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840