Protein Alignment Rm62 and Ddx4

DIOPT Version :10

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: XP_063137794.1
• Gene: Ddx4 / 310090
• RGDID: 1308793
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 699
• Identity: 222/699 - (31%)
• Similarity: 335/699 - (47%)
• Gaps: 117/699 - (16%)

  Fly    33 RSGASS---EKCITQRRHFLFSSASSSGTFASSSSLCTEQRQQFHGSRRNRETILFPSTYSSLQA 94
            |:.|||   |...:.|.||:.|..||.....:...          |....|||......:...:.
  Rat    48 RTSASSSEMEDGPSGRDHFMRSGFSSGRNLGNRDI----------GESSKRETTSTTGGFGRGKG 102

  Fly    95 QSQRAFRDSSKPDSDD---YVDSIPKAEQRTRTRKSLFND----PDERTEEIKIEGVMAPHDRDF 152
            ...|.|.::...:.|.   :.:|....|. |:||...|:.    ||....|..
  Rat   103 FGNRGFLNNKFEEGDSSGFWKESTNDCED-TQTRSRGFSKRGGYPDGNDSEAS------------ 154

  Fly   153 GHSGRGGRGGDRGGDDRRGGGGGGNRFGGGGGGGDYHGIRNGRVEKRRDDRGG---GNR------ 208
            |...|||||..||   .|||      ||.|....:|.       :.:...|||   |:|
  Rat   155 GPFRRGGRGSFRG---CRGG------FGLGRPNSEYD-------QDQGSQRGGGLFGSRKPAASD 203

  Fly   209 -----FGGGGGFGDRRGGGGGGSQDLPMRPVDFSNLAPFKKNFYQEHPNVANRSPYEVQRYR--- 265
                 .|.|..|..|.|.|.||.:.|....|..|.     ||.::........|..:..:..
  Rat   204 SVQCFTGSGDTFQSRSGNGRGGYKGLNEEVVTGSG-----KNSWKSEAEGGESSDIQGPKVTYIP 263

  Fly   266 ----EEQE-------------------ITVRG-QVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTA 306
                |:::                   :.|.| ..|..|..|.|.:|...:...|.:.||...|.
  Rat   264 PPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTP 328

  Fly   307 IQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHI-------NNQQPLQRGDGPIALVLAPTR 364
            :|....||.::|.:.:..|:||||||..::||.:.|:       :..:.||.   |..:::||||
  Rat   329 VQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQE---PECIIVAPTR 390

  Fly   365 ELAQQIQQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRC 429
            ||..||...|.:|...:.||...::||...|..:|.:.:||.|:.||||||:|.:......||:.
  Rat   391 ELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQV 455

  Fly   430 TYLVLDEADRMLDMGFEPQIRKIVS----QIRPDRQTLMWSATWPKEVKQLAEDFL-GNYIQINI 489
            .|||||||||||||||.|:::|::|    ..:..||||::|||:|:|:::||.:|| .||:.:.:
  Rat   456 KYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGEFLKSNYLFVAV 520

  Fly   490 GSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFIRSFG 554
            |.:. .|..:::|.:....::||.|||..:|.:|.|.     :.::|||||::.|.:..|:....
  Rat   521 GQVG-GACRDVQQSILQVGQYSKREKLVEILRNIGDE-----RTMVFVETKKKADFIATFLCQEK 579

  Fly   555 VRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIG 619
            :...:||||:.|.||:..|.:||.||..:||||.|||||||::.:::|||||.|...::|:||||
  Rat   580 ISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIG 644

  Fly   620 RTGRSNTKGTSFAFF-TKNNAKQAKALVDVLREANQEINPALENLARNS 667
            ||||....|.:.:|| |:::...|:.||.||.:|.|::...||.:|.:|
  Rat   645 RTGRCGNTGRAISFFDTESDNHLAQPLVKVLSDAQQDVPAWLEEIAFSS 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	166/477 (35%)
Ddx4	XP_063137794.1	None