Protein Alignment Rm62 and ddx-23

DIOPT Version :10

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_498260.2
• Gene: ddx-23 / 175818
• WormBaseID: WBGene00017162
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 694
• Identity: 207/694 - (29%)
• Similarity: 311/694 - (44%)
• Gaps: 122/694 - (17%)

  Fly    60 ASSSSLCTEQRQQFHGSRRNRETILFPSTYSSLQAQSQRAFRDSSKPDSDDYVD-SIPKAEQRTR 123
            |....|...:|......||..|......|..  ||:..|.....::..|||..| .:.:...|.|
 Worm    23 AKPKFLSKAERAALALKRREEEVAKLRETQK--QAEEARKNWGRTEKTSDDRRDRGLDRGNDRDR 85

  Fly   124 TRKSLFNDPDERTEEIKIEGVMAPHDRDFGHSGRGGRGGDRG-GDDRRGGGGGGNRFGGGGGGGD 187
            .|:. ..|.|.|.:..:..|......|.......|||..||. ..|||.......|........:
 Worm    86 DRER-ERDRDRRRDRRERSGSRDRRRRSRSRDRDGGRRRDRSRSRDRRDRNDDRKRDRNEDSDNE 149

  Fly   188 ------YHGIRNGRVEKRRDDRGGGNR-------FGGGGG-------------------FGDRRG 220
                  ...:::..:.|:::.:..|.|       |....|                   ||  ||
 Worm   150 EDVSKMADAVKDRYLGKQKEKKKRGRRLHEKKFVFDWDAGEDTSQDYNKLYQSRHEIQFFG--RG 212

  Fly   221 GGGGGSQDLPMRPVDFSNLAPFKKNFYQ---EHPNVANRSPYEVQR------------------- 263
            ...|         .|.:.....|.:|||   |:....:....|:.|
 Worm   213 SVAG---------TDVNAQKKEKNSFYQEMMENRRTVDEKEQEMHRLEKELKKEKKVAHDDRHWR 268

  Fly   264 --------------YREEQEITVR-GQVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQGWP 313
                          :||:..|::: |:||.|::::.|...||.|.:.::..||..||.||.|..|
 Worm   269 MKELSEMSDRDWRIFREDFNISIKGGRVPRPLRNWEEAGFPDEVYQAVKEIGYLEPTPIQRQAIP 333

  Fly   314 IAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGD----GPIALVLAPTRELAQQIQQVA 374
            |.:...:.:|:|:||||||..::||.:|.|.:...::|.:    ||.|:::||||||||||::..
 Worm   334 IGLQNRDVIGVAETGSGKTAAFLLPLLVWITSLPKMERQEHRDLGPYAIIMAPTRELAQQIEEET 398

  Fly   375 TEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADR 439
            .:||....::...|.|||.:..|...|:.|.|:||||||||:|.|......|.:|||::||||||
 Worm   399 NKFGKLLGIKTVSVIGGASREDQGMKLRMGVEVVIATPGRLLDVLENRYLLLNQCTYVILDEADR 463

  Fly   440 MLDMGFEPQIRKIVSQIRPD--------------------------RQTLMWSATWPKEVKQLAE 478
            ||||||||.::|:: :..||                          |||:|::||....:::||.
 Worm   464 MLDMGFEPDVQKVL-EYMPDTNMKKDTDEFDNEEALMKGFSTREKYRQTVMFTATMSSAIERLAR 527

  Fly   479 DFLGNYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRV 543
            .:|.....::|||.. .....:.|||.:..|..|.:||..:|.     |:....|||||..|:..
 Worm   528 QYLRRPAVVHIGSAG-KPTERVEQVVYMVPEDRKRKKLVEVLE-----SQFQPPIIIFVNQKKGA 586

  Fly   544 DNLVRFIRSFGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYP 608
            |.|.:.:...|.:...:||.|.|.:|::.|:..:.|.|:||||||||.||:||..:..|:|:|..
 Worm   587 DMLSKGLTKLGFKPTVLHGGKGQDQREYALQALKEGTSDILVATDVAGRGIDVKDVSLVLNYDMA 651

  Fly   609 QNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREA 652
            ::.|||.||||||||:...|.:..|.|.::......|..||.|:
 Worm   652 KSIEDYTHRIGRTGRAGKHGKAITFLTPDDTAVYFDLKQVLVES 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	166/489 (34%)
ddx-23	NP_498260.2	SrmB	304..681	CDD:440279	147/383 (38%)