Protein Alignment Rm62 and glh-3

DIOPT Version :10

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_491681.1
• Gene: glh-3 / 172245
• WormBaseID: WBGene00001600
• Length: 720
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 206/710 - (29%)
• Similarity: 309/710 - (43%)
• Gaps: 107/710 - (15%)

  Fly    38 SEKCITQRRHFLFSSASSSGTFASSSSLCTEQRQQFHGSRRNRETILFPSTYSSLQAQSQRAFRD 102
            |..||.:....|.|....|..|:..|...:|...:             |:..|..|..:.|:...
 Worm    29 SSSCIKKDDRGLSSFGVQSSVFSRRSCRMSELEAK-------------PTIISEDQRIAVRSEIG 80

  Fly   103 SSKPDSDDYVDSIPKAEQRTRTRKSLFNDPDERTEEIKIEGVMAPH---DRDFGHSGRGGRGGDR 164
            .|....||.||::      ..:..:|...|.  |.|::..|:|.|.   .|......|....|.:
 Worm    81 GSFSGFDDKVDNV------FHSNNNLHGSPS--TTELECPGIMNPRFLVGRSLNSRSRAVTRGSK 137

  Fly   165 GGDDRRGGGGGGNRFGGGGGGGDYHGIRN--GRVEKRRDDRGGGNRFGG--------------GG 213
            ...:.:...|..:|      ..|.....|  .:.|:|..|.||.:.:|.              ..
 Worm   138 RTSNVKENEGSIHR------SDDQVSTENCSAKDEERDRDSGGVSSYGNKRSDEFCGTSPILEAK 196

  Fly   214 GFG-------DRRGGGGGGSQDLPMR-------PVDFSN-LAPFKKNFYQEHPNVA--------- 254
            |||       .::.|........|.|       |...:| .|.:.||..||...|.
 Worm   197 GFGISNTCFNCKKYGHRATECSAPQRECANCGDPNHRANECASWSKNGVQEPTKVTYVPVVDKME 261

  Fly   255 --------NRSPYEVQRYREEQEITVRGQ--VPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQA 309
                    |...:..:.:....::..|||  ...|.:.||:..:|..:.:.:.|.||...|.||.
 Worm   262 EVFSMLKINAGDFFDKFFDASVQLVSRGQPVTIQPCKSFSDSDIPQSMRRNVERAGYTRTTPIQQ 326

  Fly   310 QGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQRG-DG---PIALVLAPTRELAQQI 370
            ...|:...|.:.:..|:||||||..::||.:..:..::.|..| :|   |..::|.||||||.||
 Worm   327 YTLPLVADGKDILACAQTGSGKTAAFLLPIMSRLILEKDLNYGAEGGCYPRCIILTPTRELADQI 391

  Fly   371 QQVATEFGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLD 435
            .....:|...|.:....|:||...|.....:.:||.|::.|.||:..|...|:..|.:|.|||||
 Worm   392 YNEGRKFSYQSVMEIKPVYGGINVGYNKSQIMKGCTIIVGTIGRVKHFCEDGAIKLDKCRYLVLD 456

  Fly   436 EADRMLD-MGFEPQIRKIVS----QIRPDRQTLMWSATWPKEVKQLAEDFL-GNYIQINIGSLEL 494
            |||||:| |||.|:|.:|::    .....|||:|:|||:|..|::.|...| .:|..|.|..:.
 Worm   457 EADRMIDSMGFGPEIEQIINYKNMPKNDKRQTMMFSATFPSSVQEAARKLLREDYTMITIDKIG- 520

  Fly   495 SANHNIRQVVDVCDEFSKEEKLKTLLS---DIYDTSESPG----KIIIFVETKRRVDNLVRFIRS 552
            :||..:.|..::||..||.:||..||.   |.|.|.::..    |.|:||..::..|.|...:.:
 Worm   521 AANKCVIQEFELCDRTSKVDKLLKLLGIDIDTYTTEKNSDVFVKKTIVFVAQQKMADTLASIMSA 585

  Fly   553 FGVRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHR 617
            ..|....|||.:.|.||...|:.||||...:|:||.|..||||:.|:.:|||:|.|.|.:|||||
 Worm   586 AQVPAITIHGAREQKERSAALKLFRSGAKPVLIATAVVERGLDIKGVDHVINYDMPNNIDDYIHR 650

  Fly   618 IGRTGRSNTKGTSFAFFT-KNNAKQAKALVDVLREANQEINPALENLARNSRYDGGGGRS 676
            ||||||....|.:.:|.: .::.:....||..|.:|.|.:...::..|        ||.|
 Worm   651 IGRTGRVGNSGRATSFISLADDVQILPQLVRTLADAEQVVPSWMKEAA--------GGTS 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	DEAD-like_helicase_N	231..669	CDD:475120	160/482 (33%)
glh-3	NP_491681.1	PTZ00368	182..>237	CDD:173561	8/54 (15%)
		SrmB	299..706	CDD:440279	149/413 (36%)