DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rm62 and ddx59

DIOPT Version :9

Sequence 1:	NP_524243.2	Gene:	Rm62 / 40739	FlyBaseID:	FBgn0003261	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_031756897.1	Gene:	ddx59 / 100488709	XenbaseID:	XB-GENE-976229	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	419	Identity:	146/419 - (34%)
Similarity:	235/419 - (56%)	Gaps:	12/419 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 YQEHPNVANRSPYEVQRYREEQEITVRG-QVPNPIQDFSEVHLPDYVMKEIRRQGYKAPTAIQAQ 310
            |:||..::..|..::...|::..::|.| ::..||.:|.....|..:...|:..||:.||.||.|
Frog   335 YKEHEFISQLSADQINHLRQQLSLSVHGNEMCKPIMEFDHCQFPPVLSSNIKAAGYEVPTPIQMQ 399

  Fly   311 GWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQPLQRGDGPIALVLAPTRELAQQIQQVAT 375
            ..|:.:.|.:.:..|.||||||..::||||:..     |::.|.|.||:|.||||||.||:..|.
Frog   400 MIPVGLMGRDILASADTGSGKTAAFLLPAIIRC-----LEKKDSPAALILTPTRELAVQIEGQAK 459

  Fly   376 E-FGSSSYVRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADR 439
            | .....::|...:.||.|...|:..|::|.:::|||||||::.:...|.||.....|::||||.
Frog   460 ELMRGIPHMRTALLVGGMPLPPQIHRLKQGVQVIIATPGRLLEIIKQDSVNLGDLKILIVDEADT 524

  Fly   440 MLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANHNIRQVV 504
            ||.|||:.|:..|:..:..|.||::.|||.|..::...:..|.:.::|.:|....... |:||:|
Frog   525 MLKMGFQQQVLDILEVVPHDHQTILVSATIPAGIEAFTKQLLQDPVRITVGEKNQPCT-NVRQIV 588

  Fly   505 DVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFIRSF-GVRCGAIHGDKSQSE 568
            ...:|.||::||..:|:| ....:.|  :::||:.:...|.|...:... |:.|.|:|.||||.|
Frog   589 LWVEEPSKKKKLFEILND-SKLFQPP--VLVFVDCRLGADLLSDAVSKITGLECVAMHSDKSQVE 650

  Fly   569 RDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAF 633
            |..:|:....|:.:::|:|.|..||||:..:|.|:|||.|.:.::|:|:|||.||...:||:..|
Frog   651 RMKILQGLLQGEYDVVVSTGVLGRGLDLVNVKLVVNFDMPSSMDEYVHQIGRAGRLGHRGTAITF 715

  Fly   634 FTKNNAKQAKALVDVLREANQEINPALEN 662
            ..|||......||..::.....:.|.|.|
Frog   716 INKNNRNLFWDLVKRVQPTGSLLPPQLLN 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	PTZ00424	280..656	CDD:185609	135/377 (36%)
		DEADc	283..488	CDD:238167	76/205 (37%)
		HELICc	499..633	CDD:238034	50/134 (37%)
ddx59	XP_031756897.1	PHA03247	<29..211	CDD:223021
ddx59	XP_031756897.1	PLN00206	217..759	CDD:215103	146/419 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910