Protein Alignment Rm62 and Ddx43

DIOPT Version :9

• Sequence 1: NP_524243.2
• Gene: Rm62 / 40739
• FlyBaseID: FBgn0003261
• Length: 719
• Species: Drosophila melanogaster
• Sequence 2: NP_001177973.1
• Gene: Ddx43 / 100048658
• MGIID: 3642857
• Length: 646
• Species: Mus musculus
• Alignment Length: 618
• Identity: 221/618 - (35%)
• Similarity: 326/618 - (52%)
• Gaps: 118/618 - (19%)

  Fly   155 SGRGGRGGDRGGDD---RRG-----GGGGGNR-------------------FGG---------GG 183
            |..|.||.||...:   |||     |.|||.|                   ||.         |.
Mouse    20 SSTGSRGADRTATEETNRRGRVGSRGAGGGWREPAGAAEATAAGRREPPLCFGVKNDVVGAVIGR 84

  Fly   184 GGGDYHGIRN---------------------------------GRVEKRRDDRGGGNRFGGGGGF 215
            ||.....|:|                                 ..|.|::.:...|.|. |...|
Mouse    85 GGSKIREIQNTTNTRIQVIKGNPEAEIKIFGNKAMQTKAKTVIDNVVKKQQNYIPGQRV-GIIAF 148

  Fly   216 GDRRGGGGGGSQ----DLPMRPVD-------------FSNLAPFKKNFYQEHPNVANRSPYEVQR 263
            ....|.....|:    |.|:...|             :::|.|.|||||.|....::.|..::..
Mouse   149 QPTVGADTSTSESVTDDQPLIDWDQIREDALKWEKKKWADLPPIKKNFYIESATTSSMSQVQIDN 213

  Fly   264 YREEQ-EITV-------RGQVPNPIQDFSEV--HLPDYVMKEIRRQGYKAPTAIQAQGWPIAMSG 318
            :|:|. .||.       :..:||||..|.:.  ..|: ||:.|:|.|::.||.||:|.|||.:.|
Mouse   214 WRKENFNITCDDLKDGEKRPIPNPICKFEDAFQSYPE-VMENIKRAGFQKPTPIQSQAWPIVLQG 277

  Fly   319 SNFVGIAKTGSGKTLGYILPAIVHINNQQPLQR--GDGPIALVLAPTRELAQQIQQVATEFGSSS 381
            .:.:|:|:||:||||.|::|..:|::: |||.|  .:||..|||.||||||.|::...:::   |
Mouse   278 IDLIGVAQTGTGKTLSYLMPGFIHLDS-QPLAREQRNGPGMLVLTPTRELALQVEAECSKY---S 338

  Fly   382 Y--VRNTCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGSTNLKRCTYLVLDEADRMLDMG 444
            |  :::.||:||..:.||::|:.:|.:|:|||||||.|.......|||..|||||||||:|||||
Mouse   339 YGDLKSVCVYGGGDRDGQIQDVSKGVDIIIATPGRLNDLQMNNFVNLKSVTYLVLDEADKMLDMG 403

  Fly   445 FEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANHNIRQVVDVCDE 509
            |||||.||:..:||||||:|.|||||..|::||:.:|...:.:.:|:|:|.|...::|.:.:..|
Mouse   404 FEPQIMKILLDVRPDRQTIMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIITTE 468

  Fly   510 FSKEEKLKTLLSDIYDTSESP-GKIIIFVETKRRVDNLVR--FIRSFGVRCGAIHGDKSQSERDF 571
            ..|...::|.|.::     || .|:|:||..|...|:|..  .:|...|.  ::||::.||:|:.
Mouse   469 EEKRTHIQTFLENM-----SPKDKVIVFVSRKAVADHLSSDLILRHISVE--SLHGNREQSDREK 526

  Fly   572 VLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTK 636
            .|..|::||..||:|||:|:|||||..|.:|.|:|:|:|.|:|:||:|||||:...|.|....|:
Mouse   527 ALENFKTGKVRILIATDLASRGLDVHDITHVYNYDFPRNIEEYVHRVGRTGRAGRTGMSITLITR 591

  Fly   637 NNAKQAKALVDVLREANQEINPALENLARNSRY 669
            |:.:.|..|:::|..|||.|...|..:|  .||
Mouse   592 NDWRVATELINILERANQNIPEELVLMA--ERY 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rm62	NP_524243.2	PTZ00424	280..656	CDD:185609	168/384 (44%)
		DEADc	283..488	CDD:238167	102/210 (49%)
		HELICc	499..633	CDD:238034	53/136 (39%)
Ddx43	NP_001177973.1	KH-I	73..127	CDD:238053	5/53 (9%)
		DEADc	249..446	CDD:238167	101/201 (50%)
		DEXDc	255..453	CDD:214692	100/201 (50%)
		HELICc	461..588	CDD:238034	53/133 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910