Protein Alignment CG2017 and GTPBP1

DIOPT Version :9

• Sequence 1: NP_649603.3
• Gene: CG2017 / 40733
• FlyBaseID: FBgn0037391
• Length: 643
• Species: Drosophila melanogaster
• Sequence 2: XP_016884588.1
• Gene: GTPBP1 / 9567
• HGNCID: 4669
• Length: 734
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 242/608 - (39%)
• Similarity: 350/608 - (57%)
• Gaps: 59/608 - (9%)

  Fly    55 FEEEPELNGNSSGGGSSS---SDYETDANANECSVVSGMPTERGNLIFDFEQG-MLPPEPQLGNV 115
            |..||...|.:....:::   ..:::|     ||                |.| .|..||:| ::
Human    19 FAPEPSSPGAARAAAAAARLHGGFDSD-----CS----------------EDGEALNGEPEL-DL 61

  Fly   116 EYKLKLVNPSKQRFEHLVTQMKWRLREGNGEAIYEIGVSDAGYLQGLSDKDMNASLTTLKQMAHS 180
            ..||.||:|:.::::.|:.||..|:.||.||.||.||....|...|||:.||.||..|:|.||..
Human    62 TSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQ 126

  Fly   181 LGASTSVLRRKTIAARRAVAEVLVRKIPDDQHNIEV--------RVAVLGGADAGKSTLLGVLTQ 237
            :.|...:||.:..|..| |.:.||||...|...:||        ||||:|..||||||||||||.
Human   127 IEADVILLRERQEAGGR-VRDYLVRKRVGDNDFLEVRCMGSSTRRVAVVGNVDAGKSTLLGVLTH 190

  Fly   238 DELDNGHGRARLNMFRHMHEIQSGRTSCISHETLGFDALGNVVNY--KYNEMMTAEEISDRSSKL 300
            .|||||.|.||..:|||.|||:|||||.:.::.||||:.|||||.  .:...:...:|.::|:|:
Human   191 GELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKV 255

  Fly   301 VTFMDLAGHRRYMRTTVQALSGYSPHYAMLVVSAGSGCNDTTEEHLAIVRALDMPFFVLVTKTDI 365
            :||:|||||.:|::|||..::|:.|.:.||:|.:.:|....|:|||.:..||::|.||:|||.|:
Human   256 ITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDM 320

  Fly   366 TSPDATVQE----LCNLLTTIGCRKVPFVVTNTDEAISAGSNQISENIVPIFCVSNVTGTGLNLV 426
             .|...:||    |..||.:.||||:|.:|.:.|:.|...||..||.:.|||.:|||||..|:|:
Human   321 -CPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLL 384

  Fly   427 TKFLYVLSPGISNAEKDRLEQESCEFQVDEIFRVSDVGPVVGGLLVQGVLTENMAMKIGPLPDGS 491
            ..||.:|||..|..     |:|..|||:|:.:.|..||.||.|..::|::..|..:.:||.|.|:
Human   385 KMFLNLLSPRTSYR-----EEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGN 444

  Fly   492 FHPVTVNTIHRNKAPCRVVRAGQSASLSFSMDQDVPTLRSGMVLLGDIGNSLDEPYGTFFFQAKV 556
            |..:.|.:|||.:.|.:.||.||:||.:....:. .::|.|||::....|    |..::.|:|::
Human   445 FLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKR-SSIRKGMVMVSPRLN----PQASWEFEAEI 504

  Fly   557 SVLFHATAIYVGFQTTVHIGSIRQTAVIRGIMGGERLGTNDCASVMFEFVGHPEYVRPGMRILFR 621
            .||.|.|.|...:|..||.|||||||.|.. |..:.|.|.|.|:|.|.|:..|||:....|::||
Human   505 LVLHHPTTISPRYQAMVHCGSIRQTATILS-MDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFR 568

  Fly   622 EGTSKGIGVVTQVF------PVN 638
            ||.:|.:|.:|::.      |:|
Human   569 EGRTKAVGTITKLLQTTNNSPMN 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2017	NP_649603.3	GTPBP1	100..635	CDD:227583	233/549 (42%)
		GTPBP1_like	217..436	CDD:206728	110/224 (49%)
		GTPBP_II	450..536	CDD:293895	32/85 (38%)
		GTPBP_III	547..634	CDD:294007	37/86 (43%)
GTPBP1	XP_016884588.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62195
OrthoDB	1	1.010	-	-		D305827at33208
OrthoFinder	1	1.000	-	-		FOG0002013
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100969
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820