Protein Alignment ECSIT and Ecsit

DIOPT Version :10

• Sequence 1: NP_649602.2
• Gene: ECSIT / 40732
• FlyBaseID: FBgn0028436
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_006242698.1
• Gene: Ecsit / 300447
• RGDID: 1359488
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 143/413 - (34%)
• Similarity: 220/413 - (53%)
• Gaps: 71/413 - (17%)

  Fly    37 PNPNPRAQKPGTKNLPALRNPF---AAAQDRTKNSYLTMVEIFQERDVHRRNHVEFIYAALKNMA 98
            |.|:...:||  ..:||:....   :...::.|.|:|..|..|.|.:|.:|.||:|||.||:.|.
  Rat    55 PRPSEPQKKP--IKVPAMHEDLFRPSGNGEQDKASFLNAVRSFGEHNVRKRGHVDFIYLALRKMP 117

  Fly    99 DFGVERDLEVYKALINVMPKGKFIPTNMFQAEFMHYPKQQQCIIDLLEQME--DC----GVMPDH 157
            :|||||||.||..|::|.||..|.|.|..|..|:|||:||:|.:.:|||||  .|    ||||:.
  Rat   118 EFGVERDLSVYNLLLDVFPKEVFRPRNAIQRIFVHYPRQQECGVAVLEQMERHGCASKTGVMPNT 182

  Fly   158 EMEAMLLNVFGRQGHPLRKYWRMMYWMPKFKNLSPWPLPDPVPDDTLEMAKLALERMCTVDLRSK 222
            |.|.:|:.|||.:.:|:.|:.||..|..:|||::|:|:|..:|.|.|::|||.|..| ..||.:|
  Rat   183 ETEFLLIQVFGHKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHM-EPDLSAK 246

  Fly   223 ITVFETSELKDA--IDD---TWIVSGMSPEQEKLLREHSRQKALYIEGPFHIWLRNRRINYFTLR 282
            :||::.|...::  |:|   ..||...||:|:..|..|:..:.:::||||.:||||:.:.|..||
  Rat   247 VTVYQMSLPSESTGIEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILR 311

  Fly   283 AD---ADSEFLSELDER-------QLD-----------EDDVSHIEVPFFGRAPPRRHNQLGKLR 326
            ||   .:.|.:.|:.|.       |||           |.|:..:
  Rat   312 ADLPPPEEETVEEIPEEWNLYYPMQLDLEYSRSAWDNYEFDMDEV-------------------- 356

  Fly   327 SVHQQDDGTIMAICATGTSTKDSLLSWIRLLEANGNPSIGEVPVLFRF---TSEVPAKAEEIEGG 388
                 .:|.:.|:|.||...:.:|:.||:.|:.. ||::.::||:||.   |.|:.| ...:| |
  Rat   357 -----TEGPVFAMCMTGAHDQATLVKWIQGLQET-NPTLAQIPVVFRLARSTGELLA-TTRLE-G 413

  Fly   389 ASVPATSDNSSQ--DEHISSRQK 409
            .|.|.:.....:  ||.|.::|:
  Rat   414 QSPPHSPPKGPEEDDEAIQAQQR 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECSIT	NP_649602.2	ECSIT	55..242	CDD:461857	84/200 (42%)
		PPR repeat	68..100	CDD:276811	15/31 (48%)
		PPR repeat	106..151	CDD:276811	23/46 (50%)
		PPR repeat	157..181	CDD:276811	9/23 (39%)
		ECSIT_C	245..374	CDD:464316	40/149 (27%)
Ecsit	XP_006242698.1	ECSIT	72..271	CDD:461857	84/199 (42%)
		PPR repeat	125..170	CDD:276811	23/44 (52%)
		ECSIT_C	274..398	CDD:464316	40/149 (27%)