Protein Alignment ECSIT and Ecsit

DIOPT Version :10

• Sequence 1: NP_649602.2
• Gene: ECSIT / 40732
• FlyBaseID: FBgn0028436
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_036159.1
• Gene: Ecsit / 26940
• MGIID: 1349469
• Length: 435
• Species: Mus musculus
• Alignment Length: 420
• Identity: 143/420 - (34%)
• Similarity: 220/420 - (52%)
• Gaps: 71/420 - (16%)

  Fly    27 ATDEGNPKQNPNPNPRAQKPGTKNLPALRNPF---AAAQDRTKNSYLTMVEIFQERDVHRRNHVE 88
            ||.:..|...|.| |..|:...| :||:....   :..::|.|.|:|..|..|...:|.:|.||:
Mouse    46 ATHKDEPWLVPRP-PEPQRKPIK-VPAMHEDSFKPSGNRERDKASFLNAVRSFGAHNVRKRGHVD 108

  Fly    89 FIYAALKNMADFGVERDLEVYKALINVMPKGKFIPTNMFQAEFMHYPKQQQCIIDLLEQMEDCGV 153
            |||.||:.|.:|||||||.||..|::|.||..|.|.|:.|..|:|||:||:|.:.:|||||..||
Mouse   109 FIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNVIQRIFVHYPRQQECGVAVLEQMERHGV 173

  Fly   154 MPDHEMEAMLLNVFGRQGHPLRKYWRMMYWMPKFKNLSPWPLPDPVPDDTLEMAKLALERMCTVD 218
            ||..|.|.:|:.:|||:.:|:.|:.||..|..:|||::|:|:|..:|.|.|::|||.|..| ..|
Mouse   174 MPSAETEFLLIQIFGRKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHM-EPD 237

  Fly   219 LRSKITVFETSELKDAI---DDT--WIVSGMSPEQEKLLREHSRQKALYIEGPFHIWLRNRRINY 278
            |.:|:||::.|...|:.   |.|  .||...||:|:..|..|:..:.:::||||.:||||:.:.|
Mouse   238 LSAKVTVYQMSLPSDSTGMEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYY 302

  Fly   279 FTLRAD---ADSEFLSEL---------------------DERQLDEDDVSHIEVPFFGRAPPRRH 319
            ..||||   .:.|.:.|:                     |:.:.|.|:|:
Mouse   303 HILRADLPPPEEEKVEEIPEEWELYYPQKLDLEYSRSGWDDYEFDVDEVT--------------- 352

  Fly   320 NQLGKLRSVHQQDDGTIMAICATGTSTKDSLLSWIRLLEANGNPSIGEVPVLFRF---TSEVPAK 381
                         :|.:.|:|..|...:.:|:.||:.|:.. ||::.::||:||.   |.|: ..
Mouse   353 -------------EGPVFAMCMAGAHDQATLIKWIQGLQET-NPTLAQIPVVFRLARSTGEL-LT 402

  Fly   382 AEEIEGGASVPATSDNSSQ--DEHISSRQK 409
            ...:| |.|.|.:.....:  ||.|.:.|:
Mouse   403 TSRLE-GQSPPHSPPKGPEEDDETIQAEQQ 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECSIT	NP_649602.2	ECSIT	55..242	CDD:461857	84/194 (43%)
		PPR repeat	68..100	CDD:276811	14/31 (45%)
		PPR repeat	106..151	CDD:276811	23/44 (52%)
		PPR repeat	157..181	CDD:276811	9/23 (39%)
		ECSIT_C	245..374	CDD:464316	37/152 (24%)
Ecsit	NP_036159.1	ECSIT	73..266	CDD:461857	84/193 (44%)
		PPR repeat	126..171	CDD:276811	23/44 (52%)
		ECSIT_C	269..393	CDD:464316	37/152 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..435		8/32 (25%)