Protein Alignment CG1213 and HXT1

DIOPT Version :10

• Sequence 1: NP_649599.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 536
• Identity: 136/536 - (25%)
• Similarity: 228/536 - (42%)
• Gaps: 97/536 - (18%)

  Fly    20 STFQIREGNTRTM-SPE--------------------PVKSGR-----IFMAAVAANLSAFVVGT 58
            :::::..|.::.| :||                    |..:|:     :.:..|......|:.|.
Yeast    17 NSYELESGRSKAMNTPEGKNESFHDNLSESQVQPAVAPPNTGKGVYVTVSICCVMVAFGGFIFGW 81

  Fly    59 TLGWTSPIGPK--------LKSEDTSDSPLSRPITSDEDAWISSLIAVGALVAPFVAGPMADRIG 115
            ..|..|....:        :|..|.|.. ||:..|    ..|.|:..:|..:...|...:.|..|
Yeast    82 DTGTISGFVAQTDFLRRFGMKHHDGSHY-LSKVRT----GLIVSIFNIGCAIGGIVLAKLGDMYG 141

  Fly   116 RKWVLLSSSLFFVLAFGLNMVASEVWILY-MSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGS 179
            |:..|:...:.:.:...:.:.:...|..| :.|:|.|.|||.:..:.||.:.|::...:||...|
Yeast   142 RRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVS 206

  Fly   180 LMQLFIVGGILYVYA--IGPYVSYQALQWCCIVVPVVFDLVFYM------MPESPYFFAGKGRKS 236
            ..|:.|..||...|.  .|......::|| .:.:.:.|....:|      :||||.:....||..
Yeast   207 CYQVMITLGIFLGYCTNFGTKNYSNSVQW-RVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRID 270

  Fly   237 EALKSLQFLRGQSAEG--VHDEMAEIQANVEEAMASKGTVM--DLF--KNAGNRRALFICAGLI- 294
            ||..||..:.....:.  :..|:..|:|:||| |.:.||..  :||  |.|..:|.:.   |::
Yeast   271 EARASLAKVNKCPPDHPYIQYELETIEASVEE-MRAAGTASWGELFTGKPAMFQRTMM---GIMI 331

  Fly   295 -SFQQLSGINVVLFNSQSIFASANTGLDPAIAT-IIIGCVQVGSSALTPLVADRLGRKVMLLTSS 357
             |.|||:|.|...:....:|.:  .||..:..| |:.|.|...|:..:....||.||:..|:..:
Yeast   332 QSLQQLTGDNYFFYYGTIVFQA--VGLSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGA 394

  Fly   358 SVM--------SIGLAAL-----------GAFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGFG 403
            ..|        |:|:..|           ||        |:...|.      ...|...:.|.:.
Yeast   395 VGMVCCYVVYASVGVTRLWPNGQDQPSSKGA--------GNCMIVF------ACFYIFCFATTWA 445

  Fly   404 PLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVL 468
            |:.:.|:.|.||..:||...|:.::..|..|||::||.|.:....::|..::|..|||.|:|:|.
Yeast   446 PIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYGYVFMGCMVFAYFYVF 510

  Fly   469 FVVMETKGLSLQQIQD 484
            |.|.|||||||:::.|
Yeast   511 FFVPETKGLSLEEVND 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_649599.1	MFS_GLUT6_8_Class3_like	43..481	CDD:340916	129/482 (27%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	130/485 (27%)