Protein Alignment CG1213 and ITR1

DIOPT Version :10

• Sequence 1: NP_649599.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 132/513 - (25%)
• Similarity: 234/513 - (45%)
• Gaps: 68/513 - (13%)

  Fly     4 ISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTS---- 64
            ::.|::|.|..::.:            ::||      .|......|::|.|:.|...|:.|
Yeast    66 VNDEDDTSVMITFNQ------------SLSP------FIITLTFVASISGFMFGYDTGYISSALI 112

  Fly    65 PIGPKLKSEDTSDSPLSRPITSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVL 129
            .||..|.         .:.:|..|...:::..::|||:....||..||..|||..|:.|:|.||:
Yeast   113 SIGTDLD---------HKVLTYGEKEIVTAATSLGALITSIFAGTAADIFGRKRCLMGSNLMFVI 168

  Fly   130 AFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYA 194
            ...|.:.|...|.:.:.|||.|||||....:.|:::.||:...:||....:..|::.||.|..|.
Yeast   169 GAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYG 233

  Fly   195 IGPYVSYQALQWCCIV----VP--VVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGV 253
            .|..::|....|..:|    :|  |.|..:.: :|::|.::..||..:.|.:.|:.....::|.:
Yeast   234 CGAGLNYVNNGWRILVGLSLIPTAVQFTCLCF-LPDTPRYYVMKGDLARATEVLKRSYTDTSEEI 297

  Fly   254 HDEMAEIQANVEEAMASK-------GTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQS 311
            .:...|....:.:::..|       .|:.:|.....|.|||.|..||.:.||.:|.|.:::.|.:
Yeast   298 IERKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGT 362

  Fly   312 IFASANTGLDPAIATIIIGCVQVGSSALTPLVA----DRLGRKVMLLTSSSVMSIGLAALGAFFY 372
            ||.:.......|::.|:     .|::.:..|||    |::||:.:||.....|::.|......|:
Yeast   363 IFETVGFKNSSAVSIIV-----SGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFH 422

  Fly   373 MQLVK--GDISSVV------W--MPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVA 427
            ...:|  |.::.||      |  :.:..:|::...|..|.|.:||. ..|:||.|::.:.:|...
Yeast   423 FLGIKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYALGIGTVPWQ-QSELFPQNVRGIGTSYAT 486

  Fly   428 STCWTLGFLV--TFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQ 483
            :|.|. |.||  :.|...|..:.....|..||....::..|..|...|..||.|:::|
Yeast   487 ATNWA-GSLVIASTFLTMLQNITPAGTFAFFAGLSCLSTIFCYFCYPELSGLELEEVQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_649599.1	MFS_GLUT6_8_Class3_like	43..481	CDD:340916	125/470 (27%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	121/457 (26%)