Protein Alignment CG1213 and CIN10

DIOPT Version :10

• Sequence 1: NP_649599.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_010675.3
• Gene: CIN10 / 851995
• SGDID: S000002795
• Length: 555
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 142/557 - (25%)
• Similarity: 225/557 - (40%)
• Gaps: 98/557 - (17%)

  Fly     4 ISREEETGVQYS--YTEVSTFQIREGNTRTMSPEPV--KSGRIFMAAVAANLSAFVVGTTLGWTS 64
            :|.:|...| ||  |:.:|.......|.....|..:  |:..||   |.|.:...:.|...|..|
Yeast     1 MSTDESEDV-YSDLYSIISQVTSNTANDIEQLPYALTFKTSLIF---VGATIGGLLFGYDTGVIS 61

  Fly    65 PIGPKLKSEDTSDSPLSRPITSD-EDAWISSLIAVGALVAPFVAGPMADRIGRKWVL-LSSSLFF 127
            .:...||.||     ||..:.:| :...|:|..:||:.....:|.|:|||.||:..| :..|:|.
Yeast    62 GVLLSLKPED-----LSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFI 121

  Fly   128 VLAFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYV 192
            :.|.|: .:|..:..|...||:.|..||......|:::.|||...:||...:|..:.|.||.|..
Yeast   122 LAAIGM-AIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVS 185

  Fly   193 YAIGPYV-----SYQALQWCCIVVPVVFDLVFYMMPESPYFFAGKGRKSEALKSLQFL------- 245
            |.|...:     |::.|.....:..::|..:...:||||.:...||.......||:.|
Yeast   186 YVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTY 250

  Fly   246 ----------------------------RGQSAEGVHD----------EMAEIQANVE---EAMA 269
                                        :.||.....|          .:..:.:|.|   ..|:
Yeast   251 HVNSKIKQLIIELDKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMS 315

  Fly   270 SKGTVMDLFKN-------AGNR-----------RALFICAGLISFQQLSGINVVLFNSQSIFASA 316
            |....:...:.       |.|:           |||.:...|:.|||::|.|..::.:..||:..
Yeast   316 SSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKF 380

  Fly   317 NTGLDPAIATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKGDIS 381
            |. .:|.:..|:|.......:.......|.|||:.:||.:..:|::||......|....|...:.
Yeast   381 NI-KNPLLPPILIASTNFIFTFFAMYTMDSLGRRAILLRTILIMTVGLLLCSVGFGHDQVNLLLI 444

  Fly   382 SVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPS-LD 445
            |||        ||...|.:..|.:||..: |..|.|.:|..:|.:|.|.|.....|:..|.| ::
Yeast   445 SVV--------IYVAAYASAMGSVPWTCV-EFLPLNRRSFGASCIACTNWLTNAFVSMTYLSTIN 500

  Fly   446 ALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQI 482
            .:|......:||...|.|:|||.|...|.|||||:::
Yeast   501 TIGDENTMLIFAFFTVCAWFFVYFWYPEVKGLSLEEV 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_649599.1	MFS_GLUT6_8_Class3_like	43..481	CDD:340916	131/511 (26%)
CIN10	NP_010675.3	MFS_HMIT_like	45..528	CDD:340918	123/498 (25%)