DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and HXT7

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	497	Identity:	133/497 - (26%)
Similarity:	217/497 - (43%)	Gaps:	70/497 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EPVKS--GRIFMAAVAANLSAFVV---GTTLGW-TSPIGPKLKSED----------TSDSPLSRP 83
            |||..  .|...|.|..::...::   |...|| |..|...:...|          ...:.||:.
Yeast    49 EPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKV 113

  Fly    84 ITSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWILY-MSR 147
            .|    ..|.|:..:|..:...:...:.|..|||..|:...:.:::...:.:.:...|..| :.|
Yeast   114 RT----GLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGR 174

  Fly   148 LIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYA--IGPYVSYQALQWCCIV 210
            :|.|.|||.:..:.||.:.|:|..::||...|..||.|..||...|.  .|......::|| .:.
Yeast   175 IISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQW-RVP 238

  Fly   211 VPVVFDLVFYM------MPESPYFFAGKGRKSEALKSLQFLRGQSAE--GVHDEMAEIQANVE-E 266
            :.:.|....:|      :||||.:.|..|:..||.:|:......:.:  .|..|:..:.|.|| |
Yeast   239 LGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAE 303

  Fly   267 AMASKGTVMDLFKNAGNRRALFICAGLI-SFQQLSGINVVLFNSQSIFASANTGLDPAIAT-III 329
            .:|...:..:||.:........|...:| |.|||:|.|...:...:||.:  .||..:..| |::
Yeast   304 KLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKA--VGLSDSFETSIVL 366

  Fly   330 GCVQVGSSALTPLVADRLGRKVMLLTSSSVM--------SIGLAAL-----------GAFFYMQL 375
            |.|...|:.:...|.:|.||:..||..::.|        |:|:..|           ||
Yeast   367 GIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGA------ 425

  Fly   376 VKGDISSVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFF 440
              |:...|.      ...|...:.|.:.|:|:.|:.|.||..:||.|.|:..:..|..|||:.||
Yeast   426 --GNCMIVF------ACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFF 482

  Fly   441 YPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQI 482
            .|.:....::|..::|..|:|..||:||.||.|||||:|:::
Yeast   483 TPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEV 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	129/486 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	114/459 (25%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	127/478 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	6	5.710