Protein Alignment CG1213 and RGT2

DIOPT Version :10

• Sequence 1: NP_649599.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_010143.1
• Gene: RGT2 / 851417
• SGDID: S000002297
• Length: 763
• Species: Saccharomyces cerevisiae
• Alignment Length: 527
• Identity: 148/527 - (28%)
• Similarity: 253/527 - (48%)
• Gaps: 78/527 - (14%)

  Fly     7 EEETGVQYSYTEVSTFQIREGNTRTMS-----PEPVKSG------RIFMAAVAANLSAFVVGTTL 60
            ::....|.|||  :.....:|...|.|     |.|::|.      .||:|     :..|:.|...
Yeast    60 DDPNAYQISYT--NNEPAGDGAIETTSILLSQPLPLRSNVMSVLVGIFVA-----VGGFLFGYDT 117

  Fly    61 GWTSPIG--PKLKSEDTSDSPLSRPITSDEDAWISSLIAV----GALVAPFVAGPMADRIGRK-W 118
            |..:.|.  |.:|   |..:|.....|:.:.|.:.|.:::    |||:||::    :|..||| .
Yeast   118 GLINSITDMPYVK---TYIAPNHSYFTTSQIAILVSFLSLGTFFGALIAPYI----SDSYGRKPT 175

  Fly   119 VLLSSSLFFVLAFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQL 183
            ::.|:::.|.:...|.:.:..:.:|.:.|:|.|.|:|.:..|.|:|..|.:..|:|||..|..|.
Yeast   176 IMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVVPLYQAEAAQKNLRGAIISSYQW 240

  Fly   184 FIVGGILYVYAI--------GPYVSYQ---ALQ--WCCIV-VPVVFDLVFYMMPESPYFFAGKGR 234
            .|..|:|...|:        || .||:   .||  |..|: |.::|      :||||.::..|..
Yeast   241 AITIGLLVSSAVSQGTHSKNGP-SSYRIPIGLQYVWSSILAVGMIF------LPESPRYYVLKDE 298

  Fly   235 KSEALKSLQFLRGQSAEG--VHDEMAEIQANVE-EAMASKGTVMDLFKNAGNR--RALFICAGLI 294
            .::|.|||.||||...|.  :.:|:.||:|..: ||.....|::|.||.:.||  :.|.|..|:.
Yeast   299 LNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEASFGPSTLLDCFKTSENRPKQILRIFTGIA 363

  Fly   295 --SFQQLSGINVVLFNSQSIFASANTGLDPA-IATIIIGCVQVGSSALTPLVADRLGRKVMLLTS 356
              :|||.||||.:.:...:.|  .|||:|.: :.:.|...|.|..|.....:.||:||:.:||..
Yeast   364 IQAFQQASGINFIFYYGVNFF--NNTGVDNSYLVSFISYAVNVAFSIPGMYLVDRIGRRPVLLAG 426

  Fly   357 SSVMSIG---LAALGAFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANI 418
            ..:|:|.   :|.:|......:|...|.      :..:.::...:...:|.:.|.|..|::|..:
Yeast   427 GVIMAIANLVIAIVGVSEGKTVVASKIM------IAFICLFIAAFSATWGGVVWVVSAELYPLGV 485

  Fly   419 KSVASSVVASTCWTLGFLVTFFYPSLDALGSYYA------FWLFAVCMVVAFFFVLFVVMETKGL 477
            :|..:::.|:..|.:.|......|.:..:||:.:      |:::....|||...|.|.|.||:||
Yeast   486 RSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYFAVYETRGL 550

  Fly   478 SLQQIQD 484
            :|::|.:
Yeast   551 TLEEIDE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_649599.1	MFS_GLUT6_8_Class3_like	43..481	CDD:340916	136/475 (29%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	143/505 (28%)