DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and HXT15

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_010036.1	Gene:	HXT15 / 851352	SGDID:	S000002404	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	511	Identity:	136/511 - (26%)
Similarity:	223/511 - (43%)	Gaps:	79/511 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVV---GTTLGWTSPIGPKLKSEDTSDSPLSRPI 84
            ::..|||    |:..|.|  |:..:...|..:.|   |...||.|.|.....:.|..........
Yeast    40 EVINGNT----PDAPKRG--FLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYK 98

  Fly    85 TSDEDAWISSLIAVGALVAPFVAG---------PMADRIGRKWVLLSSSLFFVLAFGLNMVASEV 140
            .|..:.::|: :.:|.|||.|..|         .:||.:||:..::...|.:::...:.:.::..
Yeast    99 HSTGEYYLSN-VRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHK 162

  Fly   141 WILY-MSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILY----VYAIGPYVS 200
            |..| :.::|.|.|.|....:.||.:.||:..::||...||.||.:..||..    ||....|.:
Yeast   163 WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSN 227

  Fly   201 YQALQW-----CCIVVPVVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEG--VHDEMA 258
              ..||     .|.:..::..:...::||||.:.....|..||..|:..:...|.|.  |..:..
Yeast   228 --TAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQAD 290

  Fly   259 EIQANV-----------EEAMASKGTVMDLFKNAGNRRALFICAGLI--SFQQLSGINVVLFNSQ 310
            ||.|.|           :|..:.|..|:..           :..|::  :|.||:|.|...|...
Yeast   291 EINAGVLAQRELGEASWKELFSVKTKVLQR-----------LITGILVQTFLQLTGENYFFFYGT 344

  Fly   311 SIFASANTGLDPAIAT-IIIGCVQVGSSALTPLVADRLG-RKVMLLTSSSVM-------SIGLAA 366
            :||.|  .||.....| |::|.|...|:.:..:|.|::| ||.:|..::|:|       |||:..
Yeast   345 TIFKS--VGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKC 407

  Fly   367 LGAFFYMQLVKGDISSVVWMPVPALIIYNIVY----CTGFGPLPWAVLGEMFPANIKSVASSVVA 427
            |    |.....|..|....   .|:|::...|    .|.:.|:.:.|:.|.||:.:||.|.|:..
Yeast   408 L----YPHGQDGPSSKGAG---NAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSIST 465

  Fly   428 STCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQ 483
            :..|...||:.||.|.:.....:|..::|..|:|..|.:|.|.:.||.||||::||
Yeast   466 AFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQ 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	128/489 (26%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	116/462 (25%)
HXT15	NP_010036.1	MFS_HXT	62..524	CDD:340914	129/483 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	6	5.710