DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and SNF3

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	525	Identity:	128/525 - (24%)
Similarity:	237/525 - (45%)	Gaps:	65/525 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSISREEETGVQYSYTEVSTFQIR--EGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTS 64
            |:..:.:.:..|.:.|.|.|..|.  :.|:...|..|.|..  .|.::...:...|.|...|:.:
Yeast    53 PTSLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQS--MMMSICVGVFVAVGGFLFGYDT 115

  Fly    65 PIGPKLKSEDTSDSPLSRPITSDEDAWISSLIAV-----------GALVAPFVAGPMADRIGRKW 118
                .|.:..||.:.:...:..:.|::.:..:::           |||.|||:    :|..|||.
Yeast   116 ----GLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALTAPFI----SDSYGRKP 172

  Fly   119 VLLSSSLF-FVLAFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQ 182
            .::.|::| |.:...|.:.|..:.:|.:.|:|.|.|:|.:..|.|:|..|.:..::|||..|..|
Yeast   173 TIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQ 237

  Fly   183 LFIVGGILYVYAI--GPYVSYQALQWCCIVVPVVFDLVF--------YMMPESPYFFAGKGRKSE 237
            ..|..|:|...|:  |.:....|..:   .:|:....|:        :.:||||.::..|.:..|
Yeast   238 WAITWGLLVSSAVSQGTHARNDASSY---RIPIGLQYVWSSFLAIGMFFLPESPRYYVLKDKLDE 299

  Fly   238 ALKSLQFLRGQSA--EGVHDEMAEIQANVE-EAMASKGTVMDLFKNAGNR----RALFICAGLIS 295
            |.|||.||||...  .|:.:|:.||:|..: ||.......:|.|.::.:|    ..:|....|.:
Yeast   300 AAKSLSFLRGVPVHDSGLLEELVEIKATYDYEASFGSSNFIDCFISSKSRPKQTLRMFTGIALQA 364

  Fly   296 FQQLSGINVVLFNSQSIFASANTGLDPA-IATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSV 359
            |||.||||.:.:...:.|  ..||:..: :.:.|...|.|..:.......:..||:.:|:....:
Yeast   365 FQQFSGINFIFYYGVNFF--NKTGVSNSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVI 427

  Fly   360 MSIGLAALGAFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGF----GPLPWAVLGEMFPANIKS 420
            |:|      |.|.:.:|...:.:|....|  :|.:..::...|    |.:.|.:..|::|..::|
Yeast   428 MTI------ANFIVAIVGCSLKTVAAAKV--MIAFICLFIAAFSATWGGVVWVISAELYPLGVRS 484

  Fly   421 VASSVVASTCWTLGFLVTFFYPSLDALGSYYA------FWLFAVCMVVAFFFVLFVVMETKGLSL 479
            ..:::.|:..|.:.|:.....|.:...||:.:      |:::.....:....|...|.|||||:|
Yeast   485 KCTAICAAANWLVNFICALITPYIVDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTL 549

  Fly   480 QQIQD 484
            ::|.:
Yeast   550 EEIDE 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	117/479 (24%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	108/452 (24%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	117/477 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I1031
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	7	6.760