DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and INT2

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_174313.1	Gene:	INT2 / 839902	AraportID:	AT1G30220	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	558	Identity:	139/558 - (24%)
Similarity:	220/558 - (39%)	Gaps:	131/558 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ANLSAFVVGTTLGWTSP----------IGPKLKSEDTSDSPLSRPI--------TSDEDAWISSL 95
            |:.|||....:|.|.:|          ||..|...||  ..:|..:        :.|.:.|:..:
plant    10 ADESAFKECFSLTWKNPYVLRLAFSAGIGGLLFGYDT--GVISGALLYIRDDFKSVDRNTWLQEM 72

  Fly    96 I----AVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWILYMSRLIQGFGVGF 156
            |    ..||:|...:.|...|::||:..:|.:...|:|...:...|....:|.:.|:..|.|||.
plant    73 IVSMAVAGAIVGAAIGGWANDKLGRRSAILMADFLFLLGAIIMAAAPNPSLLVVGRVFVGLGVGM 137

  Fly   157 VMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQALQWCCIV----VPVVFDL 217
            .....|:|:.|.|...:|||..|.....|.||....|.|....:.....|..::    :|.:...
plant   138 ASMTAPLYISEASPAKIRGALVSTNGFLITGGQFLSYLINLAFTDVTGTWRWMLGIAGIPALLQF 202

  Fly   218 V-FYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANV-----EEAMASKGTVMD 276
            | .:.:||||.:...|||:.||...|:  |..|||.|..|:..::.:|     ||..:.|..::.
plant   203 VLMFTLPESPRWLYRKGREEEAKAILR--RIYSAEDVEQEIRALKDSVETEILEEGSSEKINMIK 265

  Fly   277 LFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSI-----FASANTGLDPAIATIIIGCVQVGS 336
            |.|....||.|....||..|||..|||.|::.|.:|     |||..|.|       ::..|..|.
plant   266 LCKAKTVRRGLIAGVGLQVFQQFVGINTVMYYSPTIVQLAGFASNRTAL-------LLSLVTAGL 323

  Fly   337 SALTPLVA----DRLGRKVMLLTSSSVMSIGLAALGAFFY------------------------- 372
            :|...:::    ||:|||.:|:.|...:.|.|..|...||
plant   324 NAFGSIISIYFIDRIGRKKLLIISLFGVIISLGILTGVFYEAATHAPAISSLETQRFNNISCPDY 388

  Fly   373 -----------------------------------------------------MQLVKGDISSVV 384
                                                                 :...:|..|:..
plant   389 KSAMNTNAWDCMTCLKASSPSCGYCSSPIGKEHPGACWISDDSVKDLCHNENRLWYTRGCPSNFG 453

  Fly   385 WMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSL-DALG 448
            |..:..|.:|.|.:..|.|.:||.|..|::|...:.:...:.|:..|....:|...:.|| :|:|
plant   454 WFALLGLGLYIIFFSPGMGTVPWIVNSEIYPLRFRGICGGIAATANWISNLIVAQSFLSLTEAIG 518

  Fly   449 SYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRL 486
            :.:.|.:|.|..|:|..||:..|.||||:.:::|:..|
plant   519 TSWTFLIFGVISVIALLFVMVCVPETKGMPMEEIEKML 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	137/552 (25%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	128/530 (24%)
INT2	NP_174313.1	SP	25..552	CDD:273317	131/537 (24%)
INT2	NP_174313.1	MFS	33..541	CDD:119392	125/518 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810