DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and slc2a10

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001072926.1	Gene:	slc2a10 / 780388	XenbaseID:	XB-GENE-950490	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	545	Identity:	130/545 - (23%)
Similarity:	224/545 - (41%)	Gaps:	113/545 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLKSEDTSDSPLSRPITSDEDAWISSLIAVGAL 101
            :.|..:.:||..:.|...|.|..||..|.....||:        ...:|..|...:.|.:..|||
Frog     3 LSSPTLILAATVSLLGGIVFGYELGIISGALLVLKT--------VYQLTCFEQEALVSAVLFGAL 59

  Fly   102 VAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVA-SEVWILYMSRLIQGFGVGFVMTVQPMYV 165
            :|..:.|.:.||.||:..:|:|:| .|||..:.::| |..|.|.:.|:..||.:........:||
Frog    60 LASLIGGIIIDRWGRRTAILASNL-VVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYV 123

  Fly   166 GEISTDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQALQWCCI----VVPVVFDLV-FYMMPES 225
            .||...:.||...||.:..|..|||..||:..::|.....|..:    :||..|..: ...:|..
Frog   124 SEIVRPHQRGMLVSLYETGITVGILISYAMNYFLSGVNESWKYMFGLAIVPAAFQFISILFLPSK 188

  Fly   226 PYFFAGKGRKSEALKSLQFLRGQSAEGV--HDEMAEIQANVEEAMASKGTVMDLFKNAGNRRA-L 287
            |:             .|.|....:.:|.  .:|..|......:....:.|.:|||::..|.|. .
Frog   189 PH-------------KLNFWEQDTDDGFIELEETGEAGEFKPDTYDRQYTFLDLFRSKDNMRTRT 240

  Fly   288 FICAGLISFQQLSGINVVLFNSQSIFASA--NTGLDPAIATIIIGCVQVGSSALTPLVADRLGRK 350
            .:..||:.|||.:|...||:.:.:||.|.  .:.....:|::.:|.|:|.|:.:....||:.||:
Frog   241 LLGLGLVLFQQFTGQPNVLYYASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKAGRR 305

  Fly   351 VMLLTSSSVMSIGLAALGAFFY----------------------------MQLVKGDISSV---- 383
            ::||....||:|.:..:|...:                            :.:|..:.|::
Frog   306 ILLLAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQLLGIVHAETSTINTLD 370

  Fly   384 -----------------------------------------------VWMPVPALIIYNIVYCTG 401
                                                           .|:.:.:::.:...:..|
Frog   371 NSVHQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILNWITLLSMMAFVSAFSIG 435

  Fly   402 FGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTF-FYPSLDALGSYYAFWLFAVCMVVAFF 465
            |||:.|.||.|::||:|:..|.:...|..|....|:|. |...:.::|..:.|.|:.|..::|..
Frog   436 FGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIA 500

  Fly   466 FVLFVVMETKGLSLQQIQDRLNGKR 490
            |:.|.:.||||.||::|..:.:.||
Frog   501 FIYFFIPETKGQSLEEIDKQFSTKR 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	126/530 (24%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	115/503 (23%)
slc2a10	NP_001072926.1	MFS_GLUT10_Class3	10..517	CDD:340994	126/528 (24%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	250..256		3/5 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	528..555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920