Protein Alignment CG1213 and SLC2A3

DIOPT Version :9

• Sequence 1: NP_001246937.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 129/484 - (26%)
• Similarity: 214/484 - (44%)
• Gaps: 42/484 - (8%)

  Fly    32 MSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLKS------EDTSDSPLSRPITSDEDA 90
            |..:.|....|| |...|.:.:|..|...|..:.....:|.      .|..::|.|..:.:...:
Human     1 MGTQKVTPALIF-AITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWS 64

  Fly    91 WISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWILYMSRLIQGF 152
            ...::.:||.::..|..|...:|.||:..:|..:|..|..   .||..||..|.:|.:.||:.|.
Human    65 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129

  Fly   153 GVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYV------YAIGPYVSYQALQWCCIVV 211
            ..|......|||:||||...:|||.|:|.||.||.|||..      :.:|....:..|....|:.
Human   130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILP 194

  Fly   212 PVVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEE----AMASKG 272
            .::........||||.|.....::.|..|.:.    |...|..|...:||...:|    :...:.
Human   195 AILQSAALPFCPESPRFLLINRKEEENAKQIL----QRLWGTQDVSQDIQEMKDESARMSQEKQV 255

  Fly   273 TVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATIIIGCVQVGSS 337
            ||::||:.:..|:.:.|...|...|||||||.|.:.|..||..|.. .:|..|||..|.|....:
Human   256 TVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-QEPIYATIGAGVVNTIFT 319

  Fly   338 ALTPLVADRLGRKVM-------LLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWMPVPALIIYN 395
            .::..:.:|.||:.:       :...|::|::.|          |:|.:.:.:.::.:.|::::.
Human   320 VVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL----------LLKDNYNGMSFVCIGAILVFV 374

  Fly   396 IVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCM 460
            ..:..|.||:||.::.|:|....:..|.:|...:.||..|||...:||.......|.|.:|...:
Human   375 AFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFL 439

  Fly   461 VVAFFFVLFVVMETKGLSLQQIQDRLNGK 489
            :....|..|.|.||:|.:.:.|.....|:
Human   440 ITFLAFTFFKVPETRGRTFEDITRAFEGQ 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	125/465 (27%)
		MFS	47..460	CDD:119392	116/438 (26%)
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	123/459 (27%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		5/5 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810