DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and Glut3

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	126/503 - (25%)
Similarity:	215/503 - (42%)	Gaps:	39/503 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPI 66
            |..||:..|......:|:....:.....|    :.:.:..::.|.:.:|:.:|..|..:||:
  Fly    15 PQSSRKSGTWFAKRPSEMPERHVERAPVR----QKINNVGLYKATLYSNIGSFFFGIAVGWS--- 72

  Fly    67 GPKLKSEDTSDSPLSRPITSDEDAW--ISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVL 129
            |...:|.....|...:|   .|..|  :..|:.:||.:.....|.|...:|.:..:|...|...|
  Fly    73 GTAERSVMEQHSYSFQP---TELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFL 134

  Fly   130 AFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYA 194
            .:.|.:.|..|.:||..|...|...|....|.|:|..||||...|||.|.:.:...:.|::|.:|
  Fly   135 GWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFA 199

  Fly   195 IGPYVSYQALQWCCIVVPVVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAE 259
            :..::..:.:.:..:.:..:..|.. :|||||.::...|....|..||:|||||.    :|...|
  Fly   200 MSLFLELRIINFVNLGLLALGPLQI-LMPESPAYYVDHGNIPRAEDSLRFLRGQK----YDTRRE 259

  Fly   260 I-----QANVEEAMASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIF----AS 315
            |     .....|....:|.::. ||....||:|.....:...|:|.|..:.:|...::.    ..
  Fly   260 IDFLTRDPTESEREVRQGPLLG-FKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIR 323

  Fly   316 ANTGLDPAIATII--IGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKG 378
            ...||...:..|:  :.|.         .:.|||||:.:|:.||:.:......||..|.:.:..|
  Fly   324 REFGLILCLGLILGFLACF---------FLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMG 379

  Fly   379 DISSVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPS 443
             ::.:.|:.:..:.|:...|..|.|.|.|.:..|:....::.:..|:|.:..|...|.|..::.|
  Fly   380 -LTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGS 443

  Fly   444 LDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGKRN 491
            .......|.|.|||:...:...|.|..:.|||.||..:||.||.|..|
  Fly   444 HGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLIN 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	114/452 (25%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	106/425 (25%)
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	113/445 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	42/169 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	7	6.920