DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and CG17930

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_650533.1	Gene:	CG17930 / 41979	FlyBaseID:	FBgn0038416	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	111/525 - (21%)
Similarity:	200/525 - (38%)	Gaps:	148/525 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTT----LGWTSPIGPKLKSEDTSDSPLSRPITS 86
            :.|:|..:|...:||      .||.|.....|..    |||..             :.:|.....
  Fly    51 QSNSRWATPTQTQSG------TAATLLFVYAGMDMAQGLGWNL-------------TAVSANTLE 96

  Fly    87 DEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWI--------L 143
            .:.:|...:| :||:|:...:           ..|...:|:.|...:|::.:.:::        :
  Fly    97 FQYSWFIGVI-IGAVVSAITS-----------AFLPKIVFYGLGGVMNLIDAIIFVSAPYEYESI 149

  Fly   144 YMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQAL---Q 205
            ..:|.:.|.|:|.:.....::..||::...||...:|.|        |..|:|  |:.|.:   |
  Fly   150 LAARYVGGVGIGLITVPFLIHSAEIASSTNRGTCCALEQ--------YGLALG--VAIQVIYDSQ 204

  Fly   206 WCCIV------VPVVFDLVFYMMP--------ESPYFFAGKGRKSEALKSLQFLRGQ-------- 248
            |...:      |..:|.:||..:.        :||.|:..:.::.:|..|::.|.|.
  Fly   205 WSQGLGMTINRVHGIFGIVFTAIALGSVAITIDSPIFYIRQNQEQKARASVKQLMGSYWTREAGD 269

  Fly   249 -------------SAEGVHDEMAEIQANVEEAMASKGTVMDLFKNAGNRRALFICAGLISFQQLS 300
                         ||:||.:::.|             ::|...|     ..||.|....:|
  Fly   270 RAYDEAKLYVVEGSAQGVGEQLGE-------------SMMPFLK-----LLLFRCFVAFTF---- 312

  Fly   301 GINVVLFNSQSIFASAN--TGLDPAIATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIG 363
              :|.|  |.||..:..  .|...:..|||.|.:::..:.:|..|.|.:|||.:.|       :|
  Fly   313 --SVPL--SYSILTTTELVEGTLHSWPTIIFGLLRLIGALITFAVLDTVGRKFVSL-------LG 366

  Fly   364 LAAL-GAFFYMQLVKGDISSV-----VW----MPVPALIIYNIVYCTGFGPLPWAVLGEMFPANI 418
            |..: |....|..|.||...:     :|    :.:..........|:..     |.|||.||..:
  Fly   367 LMCMAGLMLGMAGVYGDYGHIFDDYFMWQVCRLGMAFQFFAGFFICSSS-----AYLGEAFPMRV 426

  Fly   419 KSVASSVVASTCWTLGFLVTF-FYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVM--ETKGLSLQ 480
            |.....::......:..:|.. |.|:.:   .||.::: ||.:::....|.|.|:  ||:||:|:
  Fly   427 KPFLIGLIVCLEQVIHIIVIVKFVPTAE---FYYTYFV-AVGIIMVIGLVAFAVLMPETRGLTLR 487

  Fly   481 QIQDR 485
            |..:|
  Fly   488 QAGER 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	104/504 (21%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	96/475 (20%)
CG17930	NP_650533.1	Sugar_tr	102..493	CDD:278511	97/455 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810