DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and slc2a2

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001036186.1	Gene:	slc2a2 / 322493	ZFINID:	ZDB-GENE-030131-1213	Length:	504	Species:	Danio rerio

Alignment Length:	486	Identity:	139/486 - (28%)
Similarity:	237/486 - (48%)	Gaps:	60/486 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SGRIFMAAVAANLSAFVVGTTLG------------WTSPIG----PKLKSEDTSDSPLSRPITSD 87
            :|.:.:|...|.|.:..:|.:||            :...:|    ...:||..:.:...:|  :|
Zfish     6 TGTLALAVFTAALGSLQMGYSLGVINAPQKVIERHYARSLGVYNEDLARSEGGNGTEHEKP--TD 68

  Fly    88 EDA---WISS--LIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFV---LAFGLNMVASEVWILY 144
            ...   |..|  :.:||.:::.|:...:.|..||...:|:.::..:   |..||..:.:...::.
Zfish    69 PSVVMYWSLSVAIFSVGGMLSSFLVSFVGDFRGRIKGMLAINVLAITAGLLMGLAKMGTPHLMVI 133

  Fly   145 MSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIG-PYVSYQALQWCC 208
            ..|.|.|...|....:.|:|:||||....|||.|:|.||.||.|||....|| .::......|..
Zfish   134 AGRAIMGLYCGLSSGLVPLYIGEISPVKYRGAMGALHQLAIVIGILISQVIGLDFLLGNDYMWHI 198

  Fly   209 IV----VPVVF-DLVFYMMPESP-YFFAGKGRKSEALKSLQFLRGQSAEGVHD---EMAEIQANV 264
            ::    .|.:. .|:..:.|||| |.:..:|:..:|.|||:.|:|.     :|   ::||::|..
Zfish   199 LLGLSGAPAILQSLLLLVCPESPRYLYIKQGKVEDACKSLKRLKGD-----YDTSKDIAEMKAEK 258

  Fly   265 EEAM-ASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATII 328
            |||| .:|.:::.|.:::..|:.||:...:...||.||||.:.:.|.|||.:|..| .|..|||.
Zfish   259 EEAMKEAKMSILRLLRSSVYRQQLFVALMMHFSQQFSGINAIFYYSTSIFQTAGVG-QPVYATIG 322

  Fly   329 IGCVQVGSSALTPLVADRLGRKVMLLTS-------SSVMSIGLAALGAFFYMQLVKGDISSVVWM 386
            :|.|.:..:.::.|:.||.||:.:.|..       :..|::|||..||:.:|..|     |:|
Zfish   323 VGVVNIIFTLVSVLMVDRAGRRTLTLVGLGGMCCCAVAMTVGLAFQGAYSWMSYV-----SMV-- 380

  Fly   387 PVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYY 451
               |:.::...:..|.||:||.::.|:|....:..|.::.....||..|:|...:|.|.:|...|
Zfish   381 ---AIFMFVSFFEIGPGPIPWFIVAEIFSQGPRPAAIALAGFCNWTCNFIVGMVFPYLVSLCGSY 442

  Fly   452 AFWLFAVCMVVAFFFVLFVVMETKGLSLQQI 482
            .|.:|||.:.....|:.|.|.||||.:.::|
Zfish   443 VFIVFAVLLFGFTLFIYFRVPETKGKTFEEI 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	137/481 (28%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	129/454 (28%)
slc2a2	NP_001036186.1	Sugar_tr	12..477	CDD:278511	138/480 (29%)
slc2a2	NP_001036186.1	MFS	76..462	CDD:119392	120/401 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820