DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and itr2

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_593320.1	Gene:	itr2 / 2541827	PomBaseID:	SPAC20G8.03	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	512	Identity:	125/512 - (24%)
Similarity:	224/512 - (43%)	Gaps:	48/512 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSP 65
            :||:..|||...    |:....::.:.|......|.:.|. |::.:..|.:|..:.|...|..|.
pombe    45 IPSLPNEEEANA----TDPQANEVADENGEGFEAEKISSW-IWVLSAVAGISGLLFGYDTGVISG 104

  Fly    66 IGPKLKSEDTSDSPLSRPITSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA 130
            ....|.|:      |...::|.:...|:|..:..||::...:|.:||.:|||.:||.:...||:.
pombe   105 ALAVLGSD------LGHVLSSGQKELITSATSFAALISATTSGWLADWVGRKRLLLCADAIFVIG 163

  Fly   131 FGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAI 195
            ..:...:..|.::.:.|.|.|:|:|....:.|||:.|::...:||....:..:||.||.|..|::
pombe   164 SVIMAASRNVAMMVVGRFIVGYGIGLTSLIVPMYITELAPARLRGRLVIIYVVFITGGQLIAYSL 228

  Fly   196 GPYVSYQALQWCCI----VVPVVFDLV-FYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVHD 255
            .....:....|..:    ..|.:..|: .:..||||.:........:..|.|        ..:|.
pombe   229 NAAFEHVHQGWRIMFGIGAAPALGQLISLFWTPESPRYLLRHNHVEKVYKIL--------SRIHP 285

  Fly   256 EMAEIQANVEEAMASKGTVMD----------------LFKNAGNRRALFICAGLISFQQLSGINV 304
            |....:...:.::..:|..:|                ||....|||:|||...|..|||.||.|.
pombe   286 EAKPAEIAYKVSLIQEGVKVDFPEGNKFQHFFHSLKVLFTVPSNRRSLFIGCFLQWFQQFSGTNA 350

  Fly   305 VLFNSQSIFASANTGLDPAIA-TIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALG 368
            :.:.|..||.|  .|...:|: :|::|......:.:..:..||:||:.:||.:|:||..|||...
pombe   351 IQYFSAIIFQS--VGFKNSISVSIVVGATNFVFTIVAFMFIDRIGRRRILLCTSAVMIAGLALCA 413

  Fly   369 -AFFYMQLVKGDISSVVWMPV--PALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTC 430
             |:.::.......::..|..|  .::||:...|.:|.|.:||. ..|:||..::::.:....:..
pombe   414 IAYHFLPADTTQNTNSGWQYVVLASIIIFLASYASGIGNIPWQ-QAELFPMEVRALGAGFSTAIN 477

  Fly   431 WTLGFLVT-FFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRL 486
            |....::: .|...::::.....|.|||....|......|...|..|:|::.|...|
pombe   478 WVGNLIISASFLTMMESITPTGTFALFAGFCFVGLVTSYFTYPELAGMSIENIHKLL 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	114/465 (25%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	108/438 (25%)
itr2	NP_593320.1	Sugar_tr	84..534	CDD:278511	114/466 (24%)
itr2	NP_593320.1	MFS	86..519	CDD:119392	110/449 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1095
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860