DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and ght3

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_592790.1	Gene:	ght3 / 2541758	PomBaseID:	SPAC1F8.01	Length:	555	Species:	Schizosaccharomyces pombe

Alignment Length:	471	Identity:	119/471 - (25%)
Similarity:	215/471 - (45%)	Gaps:	49/471 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VAANLSAFVVGTTLGWTSPIGPKLKSEDTSDSPLSR--PITS--DEDAW----ISSLIAVGALVA 103
            |..::|.::.|...|..|.|   |...|.......|  ||::  ...||    ::..|..|.|..
pombe    11 VFISMSGWLQGADTGSISGI---LGMRDFQSRFADRYNPISNSYSYSAWRQALLTGTINAGCLFG 72

  Fly   104 PFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWI-LYMSRLIQGFGVGFVMTVQPMYVGE 167
            ..::.|..:|||:|:.:...|..:::|..|.:.|...|| :.:.:::.|.|:|.:..:.|.|..|
pombe    73 AMLSSPFTERIGKKYSICFFSGVYIIAELLLVTAVPSWIQVLVGKILAGVGIGALSVLSPGYQSE 137

  Fly   168 ISTDNVRGATGSLMQLFIVGGILYVYAI--GPYVSYQALQW-----------CCIVVPVVFDLVF 219
            ::...:|||..:..|:|..|..|....|  |.:...:...|           ..::|.|:|
pombe   138 VAPPQIRGAVVATYQIFSTGAALVAACINMGTHKLRKTASWRTSFGINMLWGILLMVGVLF---- 198

  Fly   220 YMMPESPYFFAGKGRKSEALKSLQFLRGQSAEG--VHDEMAEIQANVEEAMA-SKGTVMDLFKNA 281
              :||||.:...|||..|||:.:..:...|.|.  :......|::::|..|| .|...:::|
pombe   199 --LPESPRYLIYKGRDEEALRIMCNMAELSPESEIIQTNFNTIKSDIEIEMAGGKARWIEIF--- 258

  Fly   282 GNRRALFICAG--LISFQQLSGINVVLFNSQSIFASANTGL-DPAIATIIIGCVQVGSSALTPLV 343
            |.......|.|  ::.|::|.|.|...:.:..:|  ..||: |..:..:|:|.:..|::......
pombe   259 GKDIRYRTCLGFLVMLFRELIGNNYYFYYATQVF--KGTGMTDIFLPAVILGAINFGTTFGALYT 321

  Fly   344 ADRLGRKVMLLTSSSVMSIGL---AALG--AFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGFG 403
            .|.|||:..|:..::..||..   ||:|  ...|........:..|.:....|.:::  ||..:|
pombe   322 IDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHRAGSVMIVFSCLFLFS--YCCSWG 384

  Fly   404 PLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVL 468
            |:.|.::||.||...:|..:||..|..|...|:::||.|.::....:...:::|...:.:.|.:.
pombe   385 PMGWVIVGETFPIRYRSKCASVATSGNWLGNFMISFFTPFINNAIGFKLGYIYACINLFSSFMIF 449

  Fly   469 FVVMETKGLSLQQIQD 484
            |:..|||||:|:::.|
pombe   450 FLAKETKGLTLEEVND 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	118/467 (25%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	110/445 (25%)
ght3	NP_592790.1	Sugar_tr	9..467	CDD:278511	119/471 (25%)
ght3	NP_592790.1	MFS	10..452	CDD:119392	112/456 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.710