DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and ght7

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001018762.2	Gene:	ght7 / 2541736	PomBaseID:	SPBC1348.14c	Length:	518	Species:	Schizosaccharomyces pombe

Alignment Length:	423	Identity:	100/423 - (23%)
Similarity:	192/423 - (45%)	Gaps:	36/423 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 TSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWI-LYMSRL 148
            :|.....|:.::.||:.....::.|:||:||::..::..:..:::...:.:.....|: :.::::
pombe    22 SSSRQGLITGMVNVGSFFGCLLSSPVADKIGKRLSIIVWTTVYLIGIIIQVTTVPSWVQILVAKI 86

  Fly   149 IQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGIL---------YVYAIGPYVSYQA- 203
            ..|..:|.:..:.|.|..|::...:|||..:..||||..||.         :.|:.|....::.
pombe    87 WTGLSIGALSVITPGYQSEVAPAIMRGAIVTTYQLFITLGIFIAACINMGTHKYSHGTTAQWRIS 151

  Fly   204 ----LQWCCI-VVPVVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEG--VHDEMAEIQ 261
                |.|..| :|.::|      :||||.:....|:..||||.:.:......|.  :..|...|:
pombe   152 IGINLLWGIITLVGIIF------LPESPRYLIAIGKDDEALKIMCYNNDLPLEHEIIQTEYHTIK 210

  Fly   262 ANVEEAMASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLD-PAIA 325
            ::.:..:|..........||..|...|:...::.||||:|.|...:....:|  ..||:| |.:|
pombe   211 SDCDAELAGGPARWPEIFNANIRYRTFLGMAVMMFQQLTGANYYFYYGTQVF--RGTGMDSPYLA 273

  Fly   326 TIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGL---AALG--AFFYMQLVKGDISSVVW 385
            .:|...|..|.:.....|.:..||:..|:.......|..   ||:|  |.::........:..|.
pombe   274 ALIPDAVNCGCTFGAIFVLEFFGRRSPLIVGGIWQYICFFIYAAVGDRALYHKNGTSNHRAGAVM 338

  Fly   386 MPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSL-DALGS 449
            :....|.|::  :...:.|..:.::||.:|...:|..::|..|..|...||::||.|.: :::|.
pombe   339 IVFSCLFIFS--FSQTWAPAAYVIVGESYPVRYRSKCAAVATSANWFWNFLISFFTPFITNSIGF 401

  Fly   450 YYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQI 482
            .|.: :||.|.:.....:...|.||||.:|::|
pombe   402 KYGY-IFASCNLTGAAIIFLFVHETKGRTLEEI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	99/421 (24%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	92/399 (23%)
ght7	NP_001018762.2	Sugar_tr	8..437	CDD:278511	100/423 (24%)
ght7	NP_001018762.2	MFS	14..422	CDD:119392	93/410 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.800