DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and ght4

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_595064.1	Gene:	ght4 / 2539710	PomBaseID:	SPBC1683.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	476	Identity:	122/476 - (25%)
Similarity:	207/476 - (43%)	Gaps:	60/476 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SAFVVGTTL-GW-----TSPIGPKLKSEDTSDSPLSR--PITS--DEDAWISSLIA----VGALV 102
            |..||..:: ||     |..|...|...|.......|  |||:  ...||..:|:.    .|.|.
pombe     7 SVLVVFISMAGWLGGADTGSISGILGMRDFQSRFADRYNPITNSYSYSAWRQALLTGTVNAGCLF 71

  Fly   103 APFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWI-LYMSRLIQGFGVGFVMTVQPMYVG 166
            ...::.|..:.||:|:.:...|..:::...|.:.|...|: :.:.:|..|..:|.:..:.|.|..
pombe    72 GAMLSSPFTEAIGKKYSIAFFSGCYIIGQILLVTAVPSWVQIMVGKLFTGLTIGALSVLSPGYQS 136

  Fly   167 EISTDNVRGATGSLMQLFIVGGILYVYAI--GPYVSYQALQW-----------CCIVVPVVFDLV 218
            |::...:|||..|..|||...|.|....|  |.:...:...|           ..::|.|:|
pombe   137 EVAPPQIRGAVVSTYQLFQTCGTLIAACINMGTHKLRKTASWRTSFGINILWGIFLMVGVLF--- 198

  Fly   219 FYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQAN-------VEEAMA-SKGTVM 275
               :||||.:...|||..|||:    :..|:|| :..|...||.|       :|..|| .|....
pombe   199 ---LPESPRYLIYKGRDEEALR----IMCQTAE-LDPESEIIQTNFNTIKSDIEMEMAGGKARWP 255

  Fly   276 DLF-KNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGL-DPAIATIIIGCVQVGSSA 338
            ::| |....|..|.....|:  ::|.|.|...:.:..:|  ..||: |..:..:|:|.:..|::.
pombe   256 EVFGKEVRYRTVLGFLTMLL--RELIGNNYYFYYATQVF--KGTGMTDIFLPAVILGAINFGTTF 316

  Fly   339 LTPLVADRLGRKVMLLTSSSVMSIGL---AALG--AFFYMQLVKGDISSVVWMPVPALIIYNIVY 398
            ......|.|||:..|:..::..||..   ||:|  ...|........:..|.:....|.:::  |
pombe   317 GALYTIDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHRAGAVMIVFSCLFLFS--Y 379

  Fly   399 CTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVA 463
            |..:||:.|.::||.||...:|..::|..|..|...|:|:||.|.:.....:...:::|...:.:
pombe   380 CCSWGPMGWVIVGETFPIRYRSKCAAVATSGNWLGNFMVSFFTPFISNSIGFKLGYIYACINMTS 444

  Fly   464 FFFVLFVVMETKGLSLQQIQD 484
            .|.:..:..|||||:|:::.:
pombe   445 AFQIFLMAKETKGLTLEEVNE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	122/472 (26%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	115/450 (26%)
ght4	NP_595064.1	Sugar_tr	9..467	CDD:278511	121/474 (26%)
ght4	NP_595064.1	MFS	10..440	CDD:119392	114/446 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.710