DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and ght5

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_587740.1	Gene:	ght5 / 2539240	PomBaseID:	SPCC1235.14	Length:	546	Species:	Schizosaccharomyces pombe

Alignment Length:	458	Identity:	107/458 - (23%)
Similarity:	212/458 - (46%)	Gaps:	43/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GW-----TSPIGPKLKSEDTSDSPLSR--PIT------SDEDAWISSLIAVGALVAPFVAGPMAD 112
            ||     |..||......|.......|  |:|      |.....|:.::.||:....|::.|:.|
pombe    17 GWMFGADTGSIGGITNMRDFQSRFADRYNPVTDSYSYSSARQGLITGMVNVGSFFGCFLSSPLMD 81

  Fly   113 RIGRKWVLLSSSLFFVLAFGLNMVASEVWI-LYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGA 176
            |||::..::..::.:::...|.:.|...|: :.::::..|..:|.:..:.|.:..|::..::||.
pombe    82 RIGKRTSIMFWTIVYLIGIILQVTAVPSWVQIMVAKIWTGLSIGALSVLAPGFQSEVAPADLRGT 146

  Fly   177 TGSLMQLFIVGGILYVYAI--GPYVSYQALQW-CCIVVPVVFDLVFYM----MPESPYFFAGKGR 234
            ..:..||.:.|||.....|  |.:..::..|| ..:.:.:::.::.::    :||||.:....||
pombe   147 IVTTYQLAVTGGIFIAACINMGTHKLHKTAQWRVSMGINLLWGIITFIGISFLPESPRYLISVGR 211

  Fly   235 KSEALKSLQFLRGQSAEGVHDEMAEIQANV------EEAMASKGTVMDLFKNAGNRRALFICAGL 293
            ..||   ||.:...:...:..|:.:.:.:|      .|......|..::| ....|...|:..|:
pombe   212 DEEA---LQIMAKNNDLPIEHEVIQTEYHVIKSDCEAELAGGPATWPEIF-GPDIRYRTFLGLGV 272

  Fly   294 ISFQQLSGINVVLFNSQSIFASANTGLD-PAIATIIIGCVQVGSSALTPLVADRLGRKVMLLTSS 357
            :|.|||:|.|...:....:|  ..||:: |.::.:|:..|..|.:.....|.:..||::.|:..:
pombe   273 MSLQQLTGDNYYFYYGFEVF--EGTGMNSPYLSALILDAVNFGCTFGGLFVLEFFGRRMPLIIGA 335

  Fly   358 SVMSIGLAALGAFFYMQLVKGDISS-----VVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPAN 417
            ...||......|.....|.:.:.:|     .|.:....|.|::  :...:||..:.::||.:|..
pombe   336 LWQSITFFIYAAVGNRALTRKNGTSNHRAGAVMIVFSCLFIFS--FAQTWGPAAYVIVGESYPIR 398

  Fly   418 IKSVASSVVASTCWTLGFLVTFFYPSL-DALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQ 481
            .:|..::|..:..|..|||::||.|.: :::|..|.: :||.|.:.|...:.....|||||:|::
pombe   399 YRSKCAAVATTGNWLWGFLISFFTPFITNSIGFKYGY-IFAACNLCAACIIFLFAHETKGLTLEE 462

  Fly   482 IQD 484
            |.:
pombe   463 INE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	106/454 (23%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	98/432 (23%)
ght5	NP_587740.1	MFS	10..451	CDD:119392	100/442 (23%)
ght5	NP_587740.1	Sugar_tr	11..467	CDD:278511	107/458 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.800