DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and ght6

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_587739.1	Gene:	ght6 / 2538845	PomBaseID:	SPCC1235.13	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	466	Identity:	118/466 - (25%)
Similarity:	206/466 - (44%)	Gaps:	61/466 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GW-----TSPIGPKLKSEDTSDSPLSR--PIT------SDEDAWISSLIAVGALVAPFVAGPMAD 112
            ||     |..||......|.......|  |:|      |.....:..::..|..|...::.|:.|
pombe    17 GWMFGADTGSIGGITNMRDFQSRYADRYDPVTDTYSYSSARQGLLVGMVNTGTTVGCLLSSPLGD 81

  Fly   113 RIGRKWVLLSSSLFFVLAFGLNMVASEVWI-LYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGA 176
            |.|::..::..:|.::....:.:.....|: :.::::..|.|:|.:..:.|.|..|.|..::|||
pombe    82 RFGKRKCIMGWTLVYITGVIVQLTTIPSWVQMMVAKIWTGLGIGALSVIAPGYQSESSPPHIRGA 146

  Fly   177 TGSLMQLFIVGGILYVYAIG----PYVSYQALQWCCIVVPVVFDLVF--------YMMPESPYFF 229
            ..:..||||..||.....|.    .|.::...||   .||:..:|::        ..:||||.:.
pombe   147 IVTTYQLFITLGIFIAACINMGTHKYTTHPEAQW---RVPIGINLLWGILMFFGMLFLPESPRYL 208

  Fly   230 AGKGRKSEALKSLQFLRGQSAEG--VHDEMAEIQANVEEAMASKGTVM--DLFKNAGNRRALFIC 290
            |.|||..|.:|.|....|..|:.  :..|...|||:||..:|. |...  .:|.|....|.| :.
pombe   209 AVKGRNEECMKILTRNAGLPADHPIMQKEYNAIQADVEAELAG-GPCSWPQIFSNEIRYRTL-LG 271

  Fly   291 AGLISFQQLSGINVVLFNSQSIFASANTGLD-PAIATIIIGCVQVGSSALTPLVADRLGRKVMLL 354
            .|:::||||:|.|...:....:|  ..|||: |.:|.:|:..|..|.:.....|.:..||:..|:
pombe   272 MGVMAFQQLTGNNYFFYYGTQVF--RGTGLNSPFLAALILDAVNFGCTFGAIFVLEYFGRRGPLI 334

  Fly   355 TSSSVMSIGLAALGAFFYMQLVKGD------------ISSVVWMPVPALIIYNIVYCTGFGPLPW 407
            ......||       .|::....||            .:..|.:....|.|::  :...:.|..:
pombe   335 VGGVWQSI-------CFFIYASVGDRALTRPNGTSNHRAGAVMIVFSCLFIFS--FAQTWAPAAY 390

  Fly   408 AVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSL-DALGSYYAFWLFAVCMVVAFFFVLFVV 471
            .::||.:|...:|..::|..::.|...|:::||.|.: :::|..|.: :||.|.:.|...:....
pombe   391 VIVGESYPIRYRSKCAAVATASNWFWNFMISFFTPFISNSIGFKYGY-VFAACNLCAAIIIFLFA 454

  Fly   472 METKGLSLQQI 482
            .|||||:|::|
pombe   455 KETKGLTLEEI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	117/464 (25%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	109/442 (25%)
ght6	NP_587739.1	MFS	10..453	CDD:119392	111/452 (25%)
ght6	NP_587739.1	Sugar_tr	11..469	CDD:278511	118/466 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16328
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.830